[en] Radioiodinated bleomycin is a useful imaging agent for body tissues. Its production by iodination of bleomycin with radioactive iodide ions in the presence of an oxidizing agent is described. 7 claims, no drawings

[en] Radioiodinated bleomycin is a useful imaging agent for body tissues. Its production by reaction of bleomycin with N-hydroxysuccinimide esters of radioiodinated hydroxyphenylalkanoic acid is described

[en] Eu²⁺ doped Sr_2-xBa_xSi₅N₈ phosphors were synthesized at 1610 ℃ for 4 h via the solid-state reaction method. The XRD results confirm that the complete solid solutions are formed. With the increase of x, the emission spectra show an obvious blue-shift from 610 nm to 585 nm under the excitation of 460 nm. The color tone can be tuned from yellow to red. The corresponding mechanism for the blue-shift of peak-wavelength is studied in detail. The results of decomposed Gaussian spectra and fluorescence lifetime show that the local coordination structure surrounding activator ions changes with increasing x value. It is found that the probability of Eu occupying Sr1 and Sr2 site is dependent on Ba/Sr ratio. The variation of thermal quenching properties and the corresponding mechanism is discussed in detail. The results indicate that Eu²⁺ doped Sr_2-xBa_xSi₅N₈ is a promising orange red-emitting phosphor for near UV or blue light-pumped white light-emitting-diodes (wLEDs). - Graphical abstract: Eu²⁺ doped Sr_2-xBa_xSi₅N₈ solid solutions were prepared by the solid-state reaction method. The structure, luminescence and thermal quenching properties with varying Ba/Sr ratio were investigated in detail. - Highlights: • The stucture and luminescence properties of Eu doped Sr_2-xBa_xSi₅N₈ phosphors were investigated. • The samples with the intermediate compositions(x=1.0,1.5) show better stability than the end members of both Sr₂Si₅N₈:Eu²⁺ and Ba₂Si₅N₈:Eu²⁺. • The possible mechanism for the improvement of thermal quenching properties was proposed.

[en] In the course of preparing peanut oil type triglycerides for metabolism studies, methyl esters of deuterated behenic acid, a saturated 22-carbon fatty acid, with zero, two, and six deuterium atoms were synthesized. The specific positions of deuterium atoms and the completion of deuteration in the products were characterized by gas chromatography/mass spectrometry methods. (author)

[en] Objective: To investigate the clinical value of the expression levels of tumor protein D52 (TPD52) and miR-133a on the prognosis assessment of pancreatic cancer surgery. Methods: This was a retrospective study. Ninety-seven patients who underwent radical surgery for pancreatic cancer in Cangzhou Central Hospital from January 2018 to January 2022 were selected and divided into four groups: TPD52 high expression group, TPD52 low expression group, miR-133a high expression group and miR-133a low expression group. The relationship between the expression levels of TPD52 and miR-133a and the clinicopathological features of patients with pancreatic cancer was analyzed. The COX regression model was used to analyze the risk factors affecting the prognosis of patients with pancreatic cancer. Results: The high expression rate of TPD52 and the low expression rate of miR-133a in pancreatic cancer tissues were higher than those in normal paracancerous tissues(P<0.05). Based on the comparison of prognosis and survival, the median survival time of patients with high expression of TPD52 and low expression of miR-133a was lower than that of patients with low expression of TPD52 and high expression of miR-133a, with a statistically significant difference(P<0.05). Moreover, multivariate Cox regression analysis showed that low differentiation of pancreatic cancer, III-IV stage of TNM, high expression of TPD52, as well as low expression of miR-133a were independent risk factors for postoperative survival of patients with pancreatic cancer(P<0.05). Conclusion: TPD52 is expressed at a high level whereas miR-133a at a low level in pancreatic cancer tissues, both of which together with low differentiation of pancreatic cancer and III-IV stage of TNM constitute independent risk factors affecting the surgical prognosis of patients with pancreatic cancer. (author)

[en] The rapidly solidified Fe-free and 15 at. % Fe-substituted Mn-Ni-Ge-based samples in the rod shape were fabricated with different diameters by the copper mould spraying casting method. Firstly, the lath martensite-like variants was strikingly observed in these compounds by the field emission scanning electron microscope (FESEM), especially in the annealed Mn-Ni-Fe-Ge samples after the mechanical and chemical treatments. It is also found that the martensite (TiNiSi-type with orthorhombic structure) coexists with the austenite (Ni₂In-type with hexagonal structure) around room temperature in the Mn-Ni-Fe-Ge compounds by the FESEM and transmission electron microscope. Resultantly, the thermomagnetic measurements shows that the single, more intimate magnetostructural transformation is achieved around room temperature for the annealed samples compared to the as-cast rods. - Highlights: • The Mn-Ni-Fe-Ge rod samples were prepared by the copper mould spraying casting method. • The lath martensitic-like variants are observed in MnNiGe-based alloys. • TEM and SAED results support strongly the co-existence of the martensite and austenite. • The magnetostructural coupling is strengthened after heat treatment.

[en] We prepared the metastable T'-phase La_2-xLn_xCuO₄ (Ln = Sm and Y) cuprates by a coprecipitation technology, which cannot be acquired by conventional solid-state reaction. The selective stabilization of T'- and T-phase was studied via altering synthesis temperature and pressure. The structural phase diagram for T- and T'-phase is obtained in La_2-xLn_xCuO₄ system. All these samples show semiconducting behavior, and no superconductivity was observed down to 2 K even after reduction. Magnetic measurement shows a Curie-Weiss-like paramagnetic behavior

[en] We have systematically measured resistivity, susceptibility and specific heat under different magnetic fields (H) in Eu_1-xLa_xFe₂As₂ single crystals. It is found that a metamagnetic transition from A-type antiferromagnetism to ferromagnetism occurs at a critical field for magnetic sublattice of Eu²⁺ ions. The jump of specific heat is suppressed and shifts to low temperature with increasing H up to the critical value, then shifts to high temperature with further increasing H. Such behavior supports the metamagnetic transition. Further, a twofold in-plane magnetization is found in antiferromagnetic state which is similar to spin density wave (SDW) order. In contrast, isotropic in-plane magnetization is presented in both ferromagnetic and paramagnetic states. Moreover, ferromagnetic state becomes more easily established under external field with suppressing SDW order. An anisotropic exchange model is proposed to understand our findings. Our results suggest that metamagnetism of Eu²⁺ ions is somewhat related to SDW order. Finally, detailed H-T phase diagrams for x=0 and 0.15 crystals are given, and possible magnetic structure is proposed.

[en] The superconducting gap in FeAs-based superconductor SmFeAs(O_1-xF_x) (x = 0.15 and 0.30) and the temperature dependence of the sample with x = 0.15 have been measured by Andreev reflection spectroscopy. The intrinsic superconducting gap is independent of contacts while many other 'gap-like' features vary appreciably for different contacts. The determined gap value of 2Δ = 13.34 ± 0.47 meV for SmFeAs(O_0.85F_0.15) gives 2Δ/k_BT_C = 3.68, close to the BCS prediction of 3.53. The superconducting gap decreases with temperature and vanishes at T_C, in a manner similar to the BCS behavior but dramatically different from that of the nodal pseudogap behavior in cuprate superconductors.

[en] Here, we report an overview of the phase-diagram of single-layered and double-layered Fe arsenide superconductors at high magnetic fields. Our systematic magneto-transport measurements of polycrystalline SmFeAsO_1-xF_x at different doping levels confirm the upward curvature of the upper critical magnetic field H_c2(T) as a function of temperature T defining the phase boundary between the superconducting and metallic states for crystallites with the ab planes oriented nearly perpendicular to the magnetic field. We further show from measurements on single-crystals that this feature, which was interpreted in terms of the existence of two superconducting gaps, is ubiquitous among both series of single- and double-layered compounds. In all compounds explored by us the zero temperature upper critical field H_c2(0), estimated either through the Ginzburg-Landau or the Werthamer-Helfand-Hohenberg single gap theories, strongly surpasses the weak-coupling Pauli paramagnetic limiting field. This clearly indicates the strong-coupling nature of the superconducting state and the importance of magnetic correlations for these materials. Our measurements indicate that the superconducting anisotropy, as estimated through the ratio of the effective masses γ = (m_c/m_ab)^1/2 for carriers moving along the c-axis and the ab-planes, respectively, is relatively modest as compared to the high-T_c cuprates, but it is temperature, field and even doping dependent. Finally, our preliminary estimations of the irreversibility field H_m(T), separating the vortex-solid from the vortex-liquid phase in the single-layered compounds, indicates that it is well described by the melting of a vortex lattice in a moderately anisotropic uniaxial superconductor.