[en] Investigation of heat transfer and friction characteristics had been conducted at atmosphere pressure on B30 horizontal circularly-grooved tube. The experimental result indicates that the circularly-grooved tube can effectively enhance the heat transfer. Within the experimental scope, the total heat transfer coefficient of the circularly-grooved tube can be increased more than 48% compared with that of the smooth tube. Through regression analysis on the experimental data, the experimental correlations for the inside heat transfer coefficient, the condensation heat transfer coefficient on film condensation and the friction coefficient were achieved. (authors)

[en] Highlights: • An nano-sized amorphous carbon covered surface was fabricated by an additive manufacturing method of SLM-IP Cu NPs. • Two layers of copper and carbon were fabricated on the substrate of stainless steel. • Steady and dynamic behaviors of droplet were tested to illustrate the super-hydrophobicity. In this paper, a nano-sized amorphous carbon covered surface was fabricated by an additive manufacturing process of selective laser melting of ink-printed (SLM-IP) copper (Cu) nanoparticles (NPs) in ambient condition. This technique synthesizes pure Cu by chemical reduction route using an organic solvent during laser melting. Additionally, the polymer in the solvent was decomposed by the thermal energy, which resulted in the formation of nano-sized amorphous carbon. Consequently, two layers of copper and carbon were fabricated on the substrate of stainless steel which was illustrated by the cross-section SEM. The upper layer of carbon possesses super-hydrophobic and high-light absorptance properties. The reaction products were characterized by the analyze of XRD, XPS and EDS. The contact angle and dynamic behavior of water droplet on the fabricated surface were carried out to demonstrate the super-hydrophobicity. The study provides an easy and flexible method for the fabrication of the functional surface by laser sintering in air ambient.

[en] objective: To master the present situation of radiation protection in some nuclear medicine workplaces and radiation workers in Hebei Province and to provide data support for strengthening radiological health supervision and developing standards related to nuclear medicine. Methods: Ambient dose equivalent rates were measured by X and gamma radiation dosimeters for 16 nuclear medicine workplaces in Hebei Province, and beta surface contamination of workplaces and staff were measured by alpha and beta surface contaminators; The deep individual dose equivalent H_p (10) of 77 nuclear medical staff was monitored by thermoluminescence dose method, and occupational health test reports of the 77 nuclear medical staff were reviewed in the recent two years. Results: There was statistical difference in the radiation level between all detection points in the SPECT (/CT) workplace (F = 32.02, P < 0.05), in which the ambient dose equivalent rates of the administration window (nurse operating position) was the highest. which was 11.92 to 37.77 μSv/h, with an average of (19.19 ± 8.78) μSv/h; There was a statistical difference in radiation levels between detection points in the PET/CT workplace (F = 56.72, P < 0.05), in which the ambient dose equivalent rates of the administration window (nurse operating position) was 14.28 to 21.55 μSv/h, with an average of (16.55 ± 3.87) μSv/h; In 16 nuclear medical workplaces, the average surface contamination level met the standard requirements. Two (12.50%) of the staff's work clothes and eight (50.00%) of their hands surface contamination level exceeded the standard in terms of surface contamination. The external exposure individual dose level of 77 nuclear medical staff was (1.11 ± 0.65) mSv. None of the 77 radiation workers were found apparent skin abnormalities, but 12 (15.58%) had some abnormalities in tissues and organs that were more sensitive to ionizing radiation. There were no significant differences found in the ocular lens abnormalities and chromosome abnormalities of the persons with exposure time of more than 20 years compared with other age groups. Conclusion: Radiation protection in the nuclear medicine workplace under investigation was in good condition, but the staff's own protection needs to be strengthened; Further attention should be paid to the occupational health management of nuclear medical personnel. (authors)

[en] A contactless non-destructive imaging method for spatially resolved dopant concentration, [2.2] N _d, and electrical resistivity, ρ, of n- and p-type silicon wafers using lock-in carrierography images at various laser irradiation intensities is presented. Amplitude and phase information from wafer sites with known resistivity was employed to derive a calibration factor for accurate determination of the absolute carrier generation rate. A frequency-domain model based on the nonlinear nature of photocarrier radiometric signals was used to extract dopant density images. Lateral variations in the resistivity of an n-type and a p-type wafer obtained by means of this methodology were found to be in excellent agreement with those obtained with conventional 4-point probe measurements. This all-optical contactless method can be used as a non-destructive tool for doping density and electrical resistivity measurements and their images over large semiconductor areas. N _d, ρ and their variances can be measured and mapped for the photovoltaic, micro- and opto-electronic industries including on wafers with oxides or surface treated layers for which contacting electrical measurements are impossible. (letter)

[en] Highlights: • Positive expression of IL-23R was observed in gastric cancer tissues and cell lines. • IL-23 promoted the migration and invasion of gastric cancer cells through STAT3. • IL-23 induced epithelial-to-mesenchymal transition of gastric cancer cells. Chronic inflammation is associated with all stages of cancer development. Moreover, a proinflammatory microenvironment resulted from chronic inflammation is considered to be an essential component of cancer. Interleukin-23 (IL-23) is a general proinflammatory factor; and is involved in tumor-associated inflammation in gastric cancer (GC). However, the direct effect of IL-23 on GC cells has been rarely reported. The aim of the study was to clarify the direct role of IL-23 in regulating GC progression, and to identify the underlying mechanism. In this study, Positive expression of IL-23R was observed in GC tissues and cell lines by using immunohistochemistry or immunofluorescence. In western blots, the expression of IL-23R was higher in GC tissues compared with adjacent normal tissues. Furthermore, IL-23R positive GC tissues were closely related with larger tumor size and worse T stage and clinical stage. By performing in vitro experiments, we found that IL-23 binding to its receptor promoted the migration and invasion of BGC-823 cells in vitro. Moreover, IL-23 induced the activation of STAT3 and epithelial-to-mesenchymal transition (EMT) in BGC-823 cells. Knocking down STAT3 in BGC-823 cells attenuated the effect of IL-23 on EMT and cell migration and invasion. Taken together, our study has firstly demonstrated the positive expression of IL-23R in human GC tissues and cell lines. IL-23 binding to its receptor promotes the migration and invasion of GC cells by inducing EMT through the STAT3 signaling pathway. This work provides a new mechanism for the oncogenic role of IL-23 on GC progression.

[en] Oil country tubular goods (OCTG) may develop plastic bending, fracture and fatigue failure during the service due to dynamic loads, such as perforation impacts and fluid-induced vibration. This paper was to evaluate strength safety of OCTG under dynamic loading. To gain key parameters of the dynamic constitutive model of materials represented by Johnson-cook. An axial tensile test of the common P110S and an experiment on its mechanical properties under high strain rate were carried out for the first time. The yield limit of P110S under static loads was 775MPa, which was 2.2% higher than the nominal value (758MPa). The ultimate strength was 835MPa and the yield ratio was 1.08. Since it often requires the yield ratio higher than 1.2 5, the P110S had slightly poor tenacity. Under the strain rates of 500s-1 and 1000s-1, the yield limits of P110S were 15.5% and 41.4% higher than the static measured values. The dynamic loading experiments of P110S under the strain rates of 500s⁻¹ and 1000s⁻¹ were corresponding to the fluid-induced vibration of columns and perforation i mpacts-induced vibration of columns, respectively. Dynamic factor of P110S was determined according to engineering habits. According to conversion and contrast analysis on increment of yield limit under dynamic loading, the final strengths were decreased by 4.5% and 8.6%, respe ctively. Moreover, key parameters of the Johnson-cook dynamic constitutive model of P110S material were determined through experiments for the first time. They could provide key para meters of constitutive model for accurate finite element simulation analysis under dynamic loa ds. (paper)

[en] We fabricated a high-performance film heater based on a silver nanowire and polymethyl methacrylate (Ag NW–PMMA) composite film, which was synthesized with the assistance of mechanical lamination and an in situ transfer method. The films exhibit excellent conductivity, high figure of merit, and strong adhesion of percolation network to substrate. By controlling NW density, we prepared the films with a transmittance of 44.9–85.0% at 550 nm and a sheet resistance of 0.13–1.40 Ω sq⁻¹. A stable temperature ranging from 130 °C–40 °C was generated at 3.0 V within 10–30 s, indicating that the resulting film heaters show a rapid thermal response, low driving voltage and stable temperature recoverability. Furthermore, we demonstrated the applications of the film heater in defrosting and a physical therapeutic instrument. A fast defrosting on the composite film with a transmittance of 88% was observed by applying a 9 V driving voltage for 20 s. Meanwhile, we developed a physical therapeutic instrument with two modes of thermotherapy and electronic-pulse massage by using the composite films as two electrodes, greatly decreasing the weight and power consumption compared to a traditional instrument. Therefore, Ag NW–PMMA film can be a promising candidate for diversified heating applications. (paper)

[en] Characterization of semiconductor surface quality is important for evaluating the surface preparation methods. In this work, three wet-cleaned silicon wafers with different surface conditions were inspected using heterodyne lock-in carrierography (HeLIC) imaging simultaneously with homodyne photocarrier radiometry (HoPCR). The surface recombination velocity was measured at various queue times after the wet-clean treatment using HeLIC and was found to be consistent with values obtained using HoPCR. The results show that HeLIC can provide a reliable quantitative imaging tool for evaluating the surface conditions of wet-cleaned silicon wafers. (paper)

[en] The increasing use of the antimicrobial triclocarban (TCC) in personal care products (PCPs) has resulted in concern regarding environmental pollution. TCC is a potent inhibitor of soluble epoxide hydrolase (sEH). Inhibitors of sEH (sEHIs) are anti-inflammatory, anti-hypertensive and cardio-protective in multiple animal models. However, the in vivo effects anticipated from a sEHI have not been reported for TCC. Here we demonstrated the anti-inflammatory effects in vivo of TCC in a murine model. TCC was employed in a lipopolysaccharide (LPS)-challenged murine model. Systolic blood pressure, plasma levels of several inflammatory cytokines and chemokine, and metabolomic profile of plasma oxylipins were determined. TCC significantly reversed LPS-induced morbid hypotension in a time-dependent manner. TCC significantly repressed the increased release of inflammatory cytokines and chemokine caused by LPS. Furthermore, TCC significantly shifted the oxylipin profile in vivo in a time-dependent manner towards resolution of inflammation as expected from a sEHI. These results demonstrated that at the doses used TCC is anti-inflammatory in the murine model. This study suggests that TCC may provide some benefits in humans in addition to its antimicrobial activities due to its potent inhibition of sEH. It may be a promising starting point for developing new low volume high value applications of TCC. However these biological effects also caution against the general over use of TCC in PCPs. - Graphical abstract: Display Omitted Research Highlights: → Anti-microbial triclocarban (TCC) is anti-inflammatory in a murine model. → TCC significantly shifted the oxylipin profile in vivo as expected from a sEHI. → TCC significantly reversed LPS-induced morbid hypotension in a time-dependent manner. → TCC significantly repressed LPS-induced increased release of inflammatory cytokines.

[en] Retrospective analysis revealed increased [${}^{18}$F]AlF-NOTA-FAPI-04 uptake in the myocardium of patients with esophageal squamous cell cancer (ESCC) treated with concurrent chemoradiotherapy (CCRT). This study investigated and verified the feasibility of [${}^{18}$F]AlF-NOTA-FAPI-04 PET/CT for detecting radiation-induced myocardial damage (RIMD). Myocardial FAPI uptake was analyzed before and during radiotherapy in thirteen ESCC patients treated with CCRT. In the animal study, a single dose of 50 Gy was delivered to the cardiac apex of Wistar rats (24 rats, including 16 RIMD model rats and 8 control model rats). RIMD model rats were scanned with [${}^{18}$F]AlF-NOTA-FAPI-04 PET/CT weekly for 12 weeks, and left ventricular ejection fraction (LVEF) was measured by magnetic resonance imaging. Dynamic, blocking, and [${}^{18}$F]FDG PET/CT studies (4 rats/group) were performed on RIMD rats at 5 weeks post-radiation, and histopathological analyses were conducted. Increased FAPI uptake in the myocardium was found after CCRT (1.53 ± 0.53 vs 1.88 ± 0.70, P = 0.015). In RIMD rats, significantly increased FAPI uptake in the damaged myocardium was observed from the 2nd week post-radiation exposure and peaked in the 5th week. Significantly more intense tracer accumulation was observed in the damaged myocardium than in the remote myocardium, as identified by decreased [${}^{18}$F]FDG uptake and confirmed by autoradiography, hematoxylin-eosin, Masson's trichrome, and immunohistochemical staining. The LVEF remained unchanged at the 3rd week post-radiation exposure but was remarkably decreased compared with that in the control group at the 8th week. Through clinical phenomena and animal experimental studies, this study indicated that [${}^{18}$F]AlF-NOTA-FAPI-04 PET/CT imaging can detect RIMD noninvasively and before a decrease in LVEF, indicating the clinical potential of [${}^{18}$F]AlF-NOTA-FAPI-04 as a PET/CT tracer for early monitoring of RIMD.