[en] An exactly solvable mean-filed plus nearest-orbit proton-proton and neutron-neutron pairing interaction model for the unified description of well-deformed nuclei in actinide region is proposed. Binding energies, pairing excitation energies, and even-odd mass differences of ^227-233Th, ^232-239U, ^236-243Pu isotopes and ²²⁸Ra-²²⁹Ac-²³⁰Th-²³¹Pa-²³²U, ²³²Th-²³³Pa-²³⁴U-²³⁵Np-²³⁶Pu, and ²³⁶U-²³⁷Np-²³⁸Pu-²³⁹Am isotones are calculated and compared with the corresponding experimental values

[en] An investigation on the equation of state of the isospin asymmetric, hot, dense matter of nucleons and deltas is performed based on the relativistic mean field theory. The QHD-II-type effective Lagrangian extending to the delta degree of freedom is adopted. Our results show that the equation of state is softened due to the inclusion of the delta degree of freedom. The baryon resonance isomer may occur depending on the delta-meson coupling. The results show that the densities for appearing the baryon resonance isomer, the densities for starting softening the equation of state and the extent of the softening depend not only on the temperature, the coupling strengths but also the isospin asymmetry of the baryon matter. (authors)

[en] An investigation on the equation of state of the isospin asymmetric, hot, dense matter of nucleons and deltas is performed based on the relativistic mean Geld theory. The QHD-Ⅱ-type effective Lagrangian extending to the delta degree of freedom is adopted. Our results show that the equation of state is softened due to the inclusion of the delta degree of freedom. The baryon resonance isomer may occur depending on the delta-meson coupling. The results show that the densities for appearing the baryon resonance isomer, the densities for starting softening the equation of state and the extent of the softening depend not only on the temperature, the coupling strengths but also the isospin asymmetry of the baryon matter. (authors)

[en] Clinically, hepatocellular carcinoma is one of the commonest malignancies. A large number of studies have shown that the genetic factor plays an important role in hepatocellular carcinoma pathogenesis. As the third generation of genetic marker, single nucleotide polymorphism is the commonest polymorphic form in human genome. At present, single nucleotide polymorphism has become an essential means for the study of the genetic susceptibility of hepatocellular carcinoma. Therefore, the further research into the single nucleotide polymorphism will be highly beneficial to the prevention, diagnosis and treatment of hepatocellular carcinoma. (authors)

[en] Objective: To investigate the inhibitory effect of sorafenib in combination use with oxaliplatin (L-OHP) on the proliferation of hepatocellular carcinoma cells and to explore the possible molecular mechanism. Methods: The inhibitory effect of sorafenib together with L-OHP on the growth of human hepatic carcinoma cell line HepG2 in vitro was evaluated by CCK8 assay. The cell cycle changes and the apoptotic rate of the treated cells were determined by flow cytometry, and the expressions of ERK and pERK were observed by using Western blott. Results: Both sorafenib and L-OHP when used alone could significantly inhibit the proliferation of HepG2 cells, and a synergistic or adding effect could by achieved when both sorafenib and L-OHP were used together (P<0.05). Sorafenib and L-OHP could cause cell cycle to stagnate at G1 phase and S phase, respectively. Combined use of the two drugs resulted in cell cycle arresting at G1 phase and S phase. The combination use of the drugs significantly increased the apoptosis rate of the cell as compared with that when only sorafenib or L-OHP was used (P<0.05). Sorafenib and L-OHP, whether used alone or in combination, did not produce obvious effect on ERK expression. However, pERK expression in the HepG2 cells was significantly lowered after the treatment with sorafenib alone or in combination with L-OHP, especially in the combination use group. Conclusion: The combination use of sorafenib and L-OHP shows a synergistic or adding effect in inhibiting the proliferation and inducing apoptosis of HepG2 cells. The mechanism of this synergistic effect may be closely related to the double blockage of the cell cycle as well as to the inhibition of Raf/MEK/ERK pathway. (authors)

[en] Sorption (distribution) coefficients of plutonium were most often derived by static batch experiments. However, it is not clear how unsaturated flow conditions including moisture content and pore water velocity change the sorption coefficients. Transport experiments of plutonium through the unsaturated sediments packed into the columns were then performed in order to determine the sorption coefficients (column-K_ds). Static batch experiments were also conducted to obtain batch-K_ds and then compare the differences between batch-K_ds and column-K_ds. The results show that unsaturated flow conditions had no significant effect on column-K_ds, and the average column-K d value was 1.74 ± 0.02 m³/kg. By comparison, batch-K_d values spanned several orders of magnitude, regardless of the specified liquid-solid conditions. Moreover, the batch-K_d (22.7 m³/kg) at the standard L/S (4 mL/g) recommended by ASTM D 4319 was over an order of magnitude larger than the average column-K_d. (author)

[en] The effect of the mass ratio of acrylamide (AM) to dimethyl dially ammonium chloride (DMDAAC) on the graft copolymerization of starch and mixtures of DMDAAC and AM was investigated at dose of 3 kGy in aqueous solution. The cationic degree of grated products is 24.3%, 19.4% and 23.1% with 0.25, 1.5 and 1.86 (W_AM: W_DM), respectively. And the graft efficiency of DMDAAC onto starch increases with the increment of the amount of AM in mixtures and the maximum value occurs at W_AM: W_DM=1.86. The total graft yield, the total graft efficiency, the monomer conversion rate and the production rate increase with the amount of AM in mixtures. (authors)

[en] Nuclear symmetry energy plays an important role in the properties of nuclei and neutron stars. Since theoretical predictions of the density dependence of symmetry energy S(ρ) from microscopic nucleon-nucleon interactions show large uncertainties, especially in the region of suprasaturation density, constraining the density dependence of symmetry energy has become one of the main goals in nuclear physics and has stimulated many theoretical and experimental studies. In this paper, we have reviewed the ImQMD05 code and its description on charge distribution, collective flow and nuclear-nuclear stopping. By comparing ImQMD05 prediction with data, the isoscalar part of nucleonic mean field, the energy and density dependence of in-medium NN cross sectoin in the ImQMD05 were determined. In order to extracting the symmetry energy information by comparing the ImQMD05 calculations with the data for ^112,124Sn +^112,124 Sn at E_beam=50 MeV/u, the influence of symmetry potential and in-medium NN cross section on the isospin sensitive observables of intermediate-energy heavy-ion collisions was investigated. Focusing on the region above the Fermi energy, our results show that the symmetry potential plays a more important role in the experimental observables, such as double neutron to proton ratio and the isospin transport ratio Ri, than that the in-medium nucleon-nucleon cross section does. Since the copious production of intermediate mass fragments is a distinguishing feature of intermediate-energy heavy-ion collisions, we also examined the influence of cluster emission on the isospin transport ratio using different isospin tracers. The values of the isospin transport ratios with the tracer defined by the isospin asymmetry of the heaviest fragments with Z≥20 in the projectile region is greater than those obtained from projectile residues (emitting source). This phenomenon can be tested experimentally. By comparing the ImQMD05 predictions with the data for three observables, the self-consistent constraints on the symmetry energy at subsaturation density were obtained. (authors)

[en] Samples of soybean meal were exposed to electron beam with dosage levels of 0, .083, 1.56, 2.30, 4.93, 7.84 kGy, to evaluate the efficacy of electron beam for decontamination as well as the effect of electron beam irradiation on feeding quality of fish meal. The results showed that the total numbers of aerobic bacteria were reduced to 600 CFU/g and fungi inhibited to < 10 CFU/g when fish meals were given an irradiation dose of 1.56 kGy. Crude protein, crude fat, moisture, ash and amino acid composition were not significantly affected with electron beam irradiation (p>0.05). Volatile basic nitrogen enhanced by electron beam irradiation (p<0.05), but no significant difference was found for the fish meal irradiated with different dosage levels (p>0.05). Total acidity value unchanged by irradiation, but peroxide value was decreased as the dosage increased (p<0.05). It was concluded that the irradiation dosage of 1.56 ∼ 7.84 kGy was very effective for microbial decontamination of fish meal, and did not adversely affect the nutritional quality of fish meal. (authors)

[en] The reaction mechanism of the central collisions and peripheral collisions for ^112,124Sn + ^112,124Sn at E/A = 50 MeV is investigated within the framework of the Improved Quantum Molecular Dynamics model. The results show that multifragmentation process is an important mechanism at this energy region, and the influence of the cluster emission on the double n/p ratios and the isospin transport ratio is important. Furthermore, three observables, double n/p ratios, isospin diffusion and the rapidity distribution of the ratio R₇ for ^112,124Sn + ^112,124Sn at E/A = 50 MeV are analyzed with the Improved Quantum Molecular Dynamics model. The results show that these three observables are sensitive to the density dependence of the symmetry energy. By comparing the calculation results to the data, the consistent constraint on the density dependence of the symmetry energy from these three observables is obtained. (author)