[en] This paper is designed to study the dispersed phase holdup in pulsed sieve plate column using experimental measurements and computational fluid dynamics simulations. The experiments and CFD simulations were conducted on 38 mm diameter pulsed sieve plate column that has standard geometry: 50 mm plate spacing, 3 mm hole diameter and 22% fractional free area. Water was used as dispersed phase with 30% tributyl phosphate-kerosene as the continuous phase. The effects of pulsed velocity, phase flow rates on the dispersed phase holdup were studied. Simulations were carried out using commercial CFD software, with standard k-ε model and Euler-Euler multiphase flow model. The simulation results were in agreements with the experiments results. (authors)

[en] Emittance is a very important parameter to accelerators. So it is valuable to measure this parameter correctly. We measured the emittance using quadrupole scan in different places in drift space in SRF gun II at ELBE and found some differences among them. But in principle, they should be the same. We have analyzed it from theory and then made some simulations to proof that is right using ASTRA and ELEGANT.

[en] The mechanism, precondition and sensitive conditions of the thermal stratification occurred in pressurized surge line was described. Three key factors influencing thermal stratification was comprehensively analyzed, including flow-rate, coolant temperature and pipeline layout. The results show that these key factors can be combined into an entirety to relieve the thermal stratification. (authors)

[en] In order to verify the safety and reliability of refueling machines under earthquake conditions, combined with ASME NOG-1 specification, the requirements of its calculation and analysis were studied, and the finite element model of the structure model of the refueling machines was established by ABAQUS. Based on the modal analysis, the seismic spectrum analysis of the refueling machines structure model was carried out by using the response spectrum of the operating platform elevation in the containment. Through the calculation, the refueling machines in the bridge, trolley and other beam-type structure and planking board, trolley plate and other shell and shell structure in the earthquake load combination of stress and displacement response were evaluated, while the refueling machine seismic calculation method was discussed at the same time. Moreover, the vibration characteristics of the structure itself and the weak links of structural instability under the action of seismic load were discussed in depth, so as to provide reference for the future engineering design and nuclear safety review. (authors)

[en] To develop a radiomics model for predicting hematoma expansion in patients with intracerebral hemorrhage (ICH) and to compare its predictive performance with a conventional radiological feature-based model. We retrospectively analyzed 251 consecutive patients with acute ICH. Two radiologists independently assessed baseline noncontrast computed tomography (NCCT) images. For each radiologist, a radiological model was constructed from radiological variables; a radiomics score model was constructed from high-dimensional quantitative features extracted from NCCT images; and a combined model was constructed using both radiological variables and radiomics score. Development of models was constructed in a primary cohort (n = 177). We then validated the results in an independent validation cohort (n = 74). The primary outcome was hematoma expansion. We compared the three models for predicting hematoma expansion. Predictive performance was assessed with the receiver operating characteristic (ROC) curve analysis. In the primary cohort, combined model and radiomics model showed greater AUCs than radiological model for both readers (all p < .05). In the validation cohort, combined model and radiomics model showed greater AUCs, sensitivities, and accuracies than radiological model for reader 2 (all p < .05). Combined model showed greater AUC than radiomics model for reader 1 only in the primary cohort (p = .03). Performance of three models was comparable between reader 1 and reader 2 in both cohorts (all p > .05). NCCT-based radiomics model showed high predictive performance and outperformed radiological model in the prediction of early hematoma expansion in ICH patients.

[en] Integral thermal-hydraulic test facilities, which have been necessary experimental platforms during the development of nuclear safety technology, could not only test and validate performance of new designed system, but also provide experimental data for development and validation of nuclear safety analysis codes. Typical integral thermal-hydraulic test facilities in the world are studied in this paper, of which the design parameters, system arrangements and functions are emphatically discussed. The results show that those integral thermal-hydraulic test facilities differ with each other in parameter scope and simulation function. Basing the fact that each facility has its advantages and disadvantages, it is better to take more factors into consideration in design of new facility. What is more, the design scheme could be optimized with new measurement technology and analysis software. (authors)

[en] Negative hydrogen Penning ion source is one of the kernel assemblies of the 11 MeV compact cyclotron. The ion yield is a key parameter of this ion source, more than 1 mA ion beam flux can be extracted from our ion source in the cyclotron, from the area of extraction slit less than 2 mm². In order to improve the strength of ion beam from the ion source, we've studied what influences can argon makes on the intensity of ion beam. The experiment measured the signal of the negative hydrogen ions when a little argon was added in. From the experiment, we know that a small quantity of argon mixed in hydrogen can efficiently advance the output of negative hydrogen ion when the arc current is the same. In addition, considered former study results of our team and theories, this article analyzed experimental data on how argon can effect the production of negative hydrogen. As a result, the addition of argon can improve the density of the vibrational hydrogen molecules, increase the form of H^-. (authors)

[en] Background: Leak-before-break technique is widely used in operating and being built nuclear plants, for which net-section-criteria is adopted by ASME to assess flawed pipes under full yielding condition. Purpose: However, net-section-criteria has been proved to overestimate the loading capacity of structure. Methods: For nuclear pipeline with internal surface crack, finite element method is used to simulate its deformation process under internal pressure, and initial plastic failure load is determined based on J integral curves of crack front. Results: Then, calculated value of initial plastic load is compared with theoretical one from ASME code, and the results show that the theoretical value overestimates the capacity load of structure. Conclusions: Finally, applicability of allowable membrane stress for level-A service restriction set by ASME-BPVC-XI code is evaluated. (authors)

[en] Catalpol, a bioactive component from the root of Rehmannia glutinosa, has been shown to possess hypoglycemic effects in type 2 diabetic animal models, however, the underlying mechanisms remain poorly understood. Here we investigated the effect of catalpol on high-fat diet (HFD)-induced insulin resistance and adipose tissue inflammation in mice. Oral administration of catalpol at 100 mg/kg for 4 weeks had no effect on body weight of HFD-induced obese mice, but it significantly improved fasting glucose and insulin levels, glucose tolerance and insulin tolerance. Moreover, macrophage infiltration into adipose tissue was markedly reduced by catalpol. Intriguingly, catalpol also significantly reduced mRNA expressions of M1 pro-inflammatory cytokines, but increased M2 anti-inflammatory gene expressions in adipose tissue. Concurrently, catalpol significantly suppressed the c-Jun NH2-terminal kinase (JNK) and nuclear factor-kappa B (NF-κB) signaling pathways in adipose tissue. Collectively, these results suggest that catalpol may ameliorate HFD-induced insulin resistance in mice by attenuating adipose tissue inflammation and suppressing the JNK and NF-κB pathways, and thus provide important new insights into the underlying mechanisms of the antidiabetic effect of catalpol. - Highlights: • Catalpol ameliorates high-fat diet (HFD)-induced insulin resistance in mice. • Catalpol reduces adipose tissue macrophage infiltration in HFD-fed mice. • Catalpol regulates M1 and M2 inflammatory gene expression in obese adipose tissue. • Catalpol suppresses the JNK and NF-κB signaling pathways in obese adipose tissue.

[en] Electrical equipment room is one of the important contents of nuclear power plant fire risk assessment. In this paper, the risk analysis of fire between electrical equipment in typical NPPs is carried out. Event tree method is used to deduce and analyze the fire scenarios and identify the hazards of fire scenarios. Finally, a fire risk assessment model is established on the basis of internal event PSA model of nuclear power plants, Fire risk quantification. Fire interpretation of the results obtained six fire scenarios, analysis of the various fire scenarios on the nuclear power plant events and system equipment. Risk quantification results show that the frequency of core damage caused by fires between electrical equipment is 1.42E-9/(reactor · year). (authors)