[en] Objective: To study the influence of hyperbaric oxygen on hypothyroidism after mi therapy. Methods: Fourty-two patients with early hypothyroidism after ¹³¹I therapy were randomly divided into two groups the hbo group (n=21) and the non-hbo group (n=21). Serum T₃, T₄4 and TSH levels were measured twice (four months apart) with CLIA in both groups. Results: Serum T₃ and T₄ levels were increased significantly in both groups after the four months course of low-dosage thyroid hormone replacement but there were no significantly differences between the final levels in the two groups (P>0.05). TSH levels were lowered significantly in both groups (both P<0.05), however, the magnitude of lowering was significantly larger in the hbo group than that in the non - hbo group (P<0.05). Conclusion: Hyperbaric oxygen therapy might be a potential useful means for treatment of early hypothyroidism after administration of ¹³¹I. (authors)

[en] The clinical application of ¹⁸FDG-PET imaging on lung cancer are introduced as well as its advantages and weaknesses are evaluated in detail. It supposes that the PET technique will be more important in diagnosis, staging, evaluation of therapeutic effect and prognosis of lung cancer

[en] EGF is labelled with ¹²⁵I or ¹³¹I, the labelling yield is 75.4% and the radiochemical purity is >95%. The animal experiments indicate that ¹²⁵I-EGF distribute mainly in liver, the kidney and spleen, and clear by kidney; the concentration of brain is lower than that of blood. It is described with a biexponential model, T_1/2α and T_1/2β are 0.3 and 80.8 min respectively. Their stability is very good

[en] Objective: To investigate the biological properties of ¹¹⁷Sn^m-triethylenetetraamine-hexa-methylene phosphonic acid (TTHMP), a new kind of bone seeking compound and to explore a potential radiopharmaceutical for target therapy of bone metastases. Methods: With the contrast of ¹¹⁷Sn^m-DTPA, the plane bone scanning on New Zealand rabbits and the biodistribution experiments on Kunming mice were performed. Results: 1) The plane bone scanning of rabbits showed that ¹¹⁷Sn^m-TTHMP was principally absorbed by skeletal system. The skull, spine and legs can be observed clearly, which was similar with the images of ¹¹⁷Sn^m-DTPA in clarity. 2) Mice experiments showed the high bone seeking of ¹¹⁷Sn^m-TTHMP. The skeletal uptakes were 15.82, 18.89 and 25.23% ID/g, respectively at 1, 4, 24 h after the injection and kept on 15.39% ID/g 14 d later. Kidney seemed to be the major excretory organ of it. The blood clearance was quick and the retention in non-target organs was low. 3) The percentage of bone uptake of ¹¹⁷Sn^m-TTHMP was higher than that of ¹¹⁷Sn^m-DTPA, and the statistical difference was significant. Conclusion: ¹¹⁷Sn^m-TTHMP shows fine biological properties which can be compared favorably with the commonly used bone radioactive agent, and it is well worth further research as a promising potential radiopharmaceutical in nuclide treatment for bone metastases

[en] Objective: To study the possible mechanism of the influence of hyperbaric oxygenation on thyroid function in mice. Methods: Fifteen mice were exposed to hyperbaric oxygen at 0.2MPa 60min daily for 10 days. Another 15 mice were exposed to hyperbaric oxygen at 0.25MPa for the same period. The mice were sacrificed afterwards and serum T₃, T₄, TSH levels determined with CLIA. Results: In both 0.2MPa group and 0.25MPa group the serum T₃ and T₄ levels were significantly higher than those in controls (15 mice) (P<0.01), but levels in the two groups were not significantly different from each other (P>0.05). The serum TSH concentrations changed little after hyperbaric oxygen exposure (P>0.05). Conclusion: HBO (0.2MPa or 0.25MPa) could enhance the thyroid secretion of T₃ and T₄, with little effect on the level of serum TSH. (authors)

[en] To reveal the correlation between the demands of network clients and the safety and robustness of real-world networks, we propose client demand centrality (CDC) in order to quantify the contributions of nodes in the transportation processes in directed weighted networks. CDC is defined by incorporating not only the topology and dynamics of the network but also the demands of network clients. The centrality measures node potential to ensure acceptable and successful transportation for clients and does quite well in distinguishing the roles of different nodes in the network. Simulation results show that node CDC has Gaussian distributions in directed networks with different link weight distributions, and the expected value of the Gaussian distribution increases from negative to positive with a decrease of the client demand. In particular, for directed scale-free networks with the scale-free link weight distribution, the network CDC is only correlated with the degree structure of the network when the client demand is large.

[en] The diversity of color and the controllability of color-gradient are both of importance for significantly expanding the practical application of outdoor superhydrophobic coating materials. Herein, a simple method has been proposed to fabricate the colorful superhydrophobic materials with metal oxides. By changing the dosages of metal oxides, the colors of the materials can be well controlled. The resultant materials with multiple colors are experimentally found to be highly robust without significant degradation in the superhydrophobicity, even after various rigorous tests. By virtue of the superior surface wetting properties, the colorful materials can be applied to separate various oil/water mixtures with high efficiency. Furthermore, the obtained materials exhibit outstanding anti-fouling property and favorable reusability, which are crucial for large-scale application of the materials. We greatly anticipate that our strategy will open a new avenue for the colorful superhydrophobic paint and coating research, and accelerate their real applications in the near future.

[en] Eutectic high entropy alloys (HEAs) are attracting considerable interest because of their excellent combination of strength and plasticity. Recently, the hypoeutectic HEAs were reported to exhibit more favorable plasticity compared with the eutectic HEAs due to the reasonable phase content and morphology. In this study, a new Fe-free Al₁₄Co₂₈Cr₂₈Ni₃₀ hypoeutectic HEA was designed by setting the molar ratio of Ni/Al and enthalpy of mixing. The alloy was composed of primary phase with a face-centered-cubic (FCC) structure and eutectic microstructure with a mixture structure of FCC and ordered body-centered-cubic (B2) phases. The FCC phase existed in both the primary dendrite phase and eutectic microstructure was enriched in Co and Cr elements, whereas the B2 phase existed in eutectic microstructure was enriched in Al and Ni elements. The present Al₁₄Co₂₈Cr₂₈Ni₃₀ hypoeutectic HEA exhibited excellent tensile property with a yield strength of 510 ± 11 MPa, an ultimate strength of 1000 ± 7 MPa and a total elongation of 21.5 ± 1.3%, which was better than most of as-cast eutectic HEAs reported previously. The findings may bring a novel insight to explore HEAs with excellent combination of strength and plasticity, and promote the HEAs’ industrial applications. (paper)

[en] This paper presents quantum bosonic shortest path searching (QBSPS), a natural, practical and highly heuristic physical algorithm for reasoning about the recognition of network structure via quantum dynamics. QBSPS is based on an Anderson-like itinerant bosonic system in which a boson's Green function is used as a navigation pointer for one to accurately approach the terminals. QBSPS is demonstrated by rigorous mathematical and physical proofs and plenty of simulations, showing how it can be used as a greedy routing to seek the shortest path between different locations. In methodology, it is an interesting and new algorithm rooted in the quantum mechanism other than combinatorics. In practice, for the all-pairs shortest-path problem in a random scale-free network with N vertices, QBSPS runs in O(μ(N) ln ln N) time. In application, we suggest that the corresponding experimental realizations are feasible by considering path searching in quantum optical communication networks; in this situation, the method performs a pure local search on networks without requiring the global structure that is necessary for current graph algorithms.

[en] An experimental investigation on flow past nine cylinders in a square configuration was carried out using the particle image velocimetry technique and load cell in a water channel. The center-to-center spacing ratio L/D was in the range of 1.5–3.0 and the Reynolds number Re was varied from 1500 to 5000. The effects of spacing ratio and Reynolds number on the instantaneous time-averaged flow fields and force coefficients are investigated. The results show that three distinct flow regimes are categorized with variation of the spacing ratios and Reynolds numbers, namely, shielding flow regime, transition flow regime and vortex shedding flow regime. Depending on the interferences of shear layers around the nine cylinders, each flow regime is further divided into two types of flow patterns. An interesting feature of bistable flow pattern with different flow modes is observed at small spacing ratio L/D = 1.5. The non-dimensional vortex shedding frequencies appear to be more associated with the individual shear layers rather than the multiple cylinders. Moreover, force analysis, streamline topologies and Reynolds stress contours are presented to elucidate the effects of spacing ratio and Reynolds number on the complex wake interference among the nine cylinders. The flow characteristics and force coefficients are found to be more sensitive to L/D rather than Re. (paper)