[en] Recent investigations by the Atomic Minerals Directorate for Exploration and Research, have brought into focus the presence of uranium mineralisation hosted by granite in its fracture zones, close to the unconformity in the Srisailam outliers in Lambapur, Peddagattu and Chitrial areas in the northern part of Cuddapah basin. Investigations further east of the Srisailam sub-basin have revealed good uranium mineralisation, both at the unconformity and in the overlying sediments of Banganapalle Formation of Kurnool Group in the Palnad sub-basin, around Koppunuru-Dwarakapuri. Further investigations southwest of these areas in the Kurnool sub-basin, have revealed significant uranium mineralisation in the Banganapalle Quartzite, intruded by vein quartz, close to the Gani-Kalva fault. This uranium discovery in the Kurnool sub-basin and some of its salient features, which have enhanced the uranium potentiality of the sub-basin as well as along the Gani-Kalva fault zone (55 km length and 2 km width) are reported here