No abstract available

No abstract available

[en] Development of biodegradable polyester nanoparticles have been extensively explored for use in drug delivery systems. This paper describes the methods utilized to form palm oil-based polyester nanoparticles using gamma radiation grafting technique and describes the obtaining nanoparticles physiochemical properties. The radiation grafting method can be used to obtain palm oil-based polyester nanoparticles with the particle sizes in the range of 60 to 100 nm with a small particle size distribution, which the particle sizes and images can be investigated using dynamic light scattering (DLS) and transmission electron microscopy (TEM). The chemical functional group of nanoparticles can be investigated by Fourier transform infrared (FTIR) spectroscopy analysis. This research study can contribute to ensure success in production of promising palm oil-based polyester nanoparticles for use in drug delivery system. (author)

[en] Obtaining high purity of xylitol is a stone corner in medicine industries. Many conventional techniques (crystallization and adsorption) were used for xylitol purification from fermentation media. Recently, membrane technology received a great attention due to its high performance in xylitol purification. Among renowned copolymers used for polymer blending to produce membranes, pluronic is receiving much attention due to its strong hydrophilic characteristic and could work as pore former and surface modifier. Polyethersulfone (PES) polymer has been reportedly used for polymer blending as it possesses mechanical and chemical stabilities. Therefore, this work demonstrates the preparation of nanofiltration (NF) membrane using: (1) PES and (2) PES blended with 1.71 % and 5 % of Pluronic (F127), via phase inversion method. All fabricated membranes were subjected to investigations such as contact angle for hydrophilicity and water and solution flux for membrane performance. The findings showed increasing in water flux from 24.6 L/m².h to 70.2 L/m².h as 5 % of Pluronic added. Further, the hydrophilicity improved from 80.1±1.93 degree to 72±0.3 degree and 67.6±0.72 degree when 1.71 and 5 % of Pluronic F127 added respectively. Therefore, the addition of Pluronic f127 has a great impact on PES membrane for xylitol permeation. (author)

[en] The polymeric nanoparticles (NPs) with desirable structures and properties extracted from palm oil by using the gamma radiation-induced reversible-addition fragmentation chain transfer (RAFT) polymerisation and crosslinking technique. The raw materials of acrylated palm olein (APO) and polyol ester were used to create nanoparticle-based drug delivery systems. The gamma radiation-induced RAFT offers a promising method to produce NPs with size of less than 150 nm and low molecular weight of 23,982 Da. The crosslinked poly(APO-b-polyol ester) copolymer NPs was determined as biodegradable, amorphous, and had good thermal properties as assessed by FTIR, XRD, DSC and TGA analyses. The discovery implied that radiation processing technology could be used to prepare and obtain the desired nanocarriers. (author)

[en] The radiation processing is widely used for the development of innovative technologies and advanced products for different branches of the manufacturing sector. Polymeric nanoparticles (NPs) with desirable structures and properties made from palm oil is produced by utilization of the gamma radiation-induced reversible-addition fragmentation chain transfer (RAFT ) polymerization and crosslinking technique for designing the nanocarrier. The polymeric nanoparticles were found to possess biodegradable, amorphous and, good thermal properties which made them highly suitable for the design of the drug delivery system. (author)