[en] To assess Carpal tunnel syndrome (CTS) presence and its associated factors in third trimester of pregnancy. Methodology: By using convenient sampling this cross-sectional study of 150 Patients was done in 6 months at Madinah teaching Hospital and Allied Hospital, Faisalabad. Boston Carpal tunnel questionnaire, Tinel's test and Phalen's test were used. Data were analyzed through SPPS version 20. Result: Out of 150 females, Only 24(16%) had CTS symptoms measured through Tinel's test and Phalen's test. There was no significant association (P=0.179) between CTS and third trimester of pregnancy. CTS occurrence was not associated (P=0.251) with age of patient. Conclusion: The study shows low presence of CTS in third trimester of pregnancy. Moreover, there is no significant association exists among age of patient, month of pregnancy and carpal tunnel syndrome. CTS can occur at any age and during any month of pregnancy. (author)

[en] Objective: To determine the frequency of cerebral aneurysm in patients with subarachnoid haemorrhage on CT cerebral angiography. Methods: This prospective cross-sectional study was conducted at Department of Radiology, JPMC, Karachi from 5th June 2022 to 30th January 2023. Total 176 patients with subarachnoid haemorrhage irrespective of gender were selected. CT angiography of cerebral vessels was performed. Cerebral aneurysm was noted as per operational definition and recorded. Results: Age range was from 18 to 60 years. Mean age was 39.516±6.77 years, Mean BMI 29.630±3.08 Kg/m2. and mean duration of symptoms was 7.721±2.40 days. Male patients were 80.1% and females were 19.9%. Cerebral aneurysm was observed in 91.4% female and 78.7% male patients. Aneurysmal percentage was slightly higher in younger (18-40 years) age group (84.2% vs 80.4%) as compared to older (40-60) age group but statistically not significant. Although total percentage of female was quite less 19.9% (n=35 vs n=141 male), in this lesser female percentage, aneurismal detection was higher as compared to male gender (91.4% vs 78.7%). Distribution of aneurysms according to vessel involved was; 28.7% along anterior communicating artery, 28.3% related to middle cerebral artery and, 22.9% were along posterior communicating vessel. Rest was distributed among other vessels including tip of basilar artery. Conclusion: In Our study aneurysms was seen 81.3% in patients of subarachnoid hemorrhage having CT angiography at our center in Karachi Pakistan. (author)

[en] A 53-year-old man with a 3-day history of periorbital swelling and vision loss in the left eye was found to have septic cavernous sinus thrombosis with bilateral orbital vein involvement causing congestive orbitopathy. He was treated with an emergent canthotomy and cantholysis, intraocular pressure-lowering drops, antibiotics, anticoagulation, and serial examinations. Optical coherence tomography ultimately revealed diffuse ischemic destruction of both layers of the retina, which suggested occlusion of the ophthalmic artery or the short posterior ciliary arteries and central retinal artery without intracavernous internal carotid artery involvement. The patient remained without light perception in the left eye after treatment. (author)

[en] In a joint project between The Norwegian Petroleum Directorate (NPD), the State Pollution Control Agency (SFT) and Conoco Norway Inc. (CNI) we have evaluated the use of quality assurance principles in connection with development and distribution of information about chemicals. Assuring quality of the documentation is first of all depending on: the work in international organizations; the content of national and international guidelines and criteria documents; the use of product registers; activities in manufacturers' organizations; the role of importers and agents. These are aspects which have been evaluated. Recommendations are given in this paper concerning: definition of responsibilities in regulations, standards and guidelines; feedback of experience and coordination through international work; application of quality assurance principles in the use of information technology in international organizations and in manufacturers' organizations; use of quality assurance principles in validation of data

[en] Enaminones; 4-N,N-diethylamine-pent-3-ene-2-one [HL1], 4-N,N-di-n-propylamine-pent-3-ene-2-one [HL2] and 4-N,N-dicyclohexylamine-pent-3-ene-2-one [HL3] and their complexes with Ni (II) and Sb (III) ions were prepared by reacting the equimolar ethanolic solutions of the ligands (HL1, HL2 and HL3) with ethanolic metal ion solutions. The synthesized metal complexes were characterized by infrared, UV/Visible and atomic absorption spectroscopy. Metal complexes of Ni (II) and Sb (III) ions thus prepared, showed coordination numbers, four and six respectively. They were tested for their antibacterial activity against Escherichia coli and Staphylococcus aureus, staphylococcus epidermidis bacteria. Ligands were completely inactive against bacteria whereas the complexes of Sb (III) with ligands (HL/sub 1/, HL/sub 2/ and HL/sub 3/) have remarkable action on these bacteria, indicating that they have an ample potency as bactericide. Other complexes have normal bactericidal character. (author)