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AbstractAbstract
[en] Aerosol inhalation cine-scintigraphy which is a new method for estimation of mucociliary clearance, was studied in patients with diffuse panbronchiolitis (DPB), pulmonary emphysema (PE), chronic bronchitis (CB) and normal controls. The deposition pattern of inhaled aerosols showed mainly a central pattern in PE, but mainly a peripheral pattern in DPB. According to serial observation of inhaled aerosols by cine-scintigraphy, tracheal transport of aerosol-bolus was in a cephalad direction and moved smoothly in normal controls, but transport was slow, zigzag and sometimes regurgitant in patients with PE and CB. Especially, no transport was observed in patients with DPB. Therefore, the authors considered that DPB had the worst impairment of mucociliary clearance, because of both ciliary abnormality and rheological disorders, in the diseases of respiratory tract. (author)
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Record Type
Journal Article
Journal
Nippon Kyobu Shikkan Gakkai Zasshi; ISSN 0301-1542; ; v. 22(6); p. 479-485
Country of publication
AEROSOLS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BODY, CLEARANCE, COLLOIDS, COUNTING TECHNIQUES, DIAGNOSTIC TECHNIQUES, DISEASES, DISPERSIONS, EXCRETION, HOURS LIVING RADIOISOTOPES, INTAKE, INTERMEDIATE MASS NUCLEI, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, NUCLEI, ODD-EVEN NUCLEI, ORGANS, PATHOLOGICAL CHANGES, RADIOISOTOPE SCANNING, RADIOISOTOPES, RESPIRATORY SYSTEM, RESPIRATORY SYSTEM DISEASES, SOLS, TECHNETIUM ISOTOPES, YEARS LIVING RADIOISOTOPES
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