[en] Published in summary form only

[en] The types of nuclear reactions for radioisotope production using nuclear reactors and cyclotrons are described. The question of purity and quality control of the products are discussed. (M.C.K.)

[en] The reaction between lanthanide perchlorates and yttrium with tetra methyl phthalamide (TMPA) was studied, and compounds of the general formula Ln (C 10 ₄) ₃. TMPA have been isolated. The compounds were characterized by analysis of their components, infra-red spectra, molar conductances in nitromethane and nitrobenzene, X ray powder patterns and thermal analysis. (author)

[en] A radiochemical method to isolate ⁹⁹Mo from ¹³²Te both produced in the fission of ²³⁵U has been developed. The methods is based on the formation of a cationic complex of tellerium with thiourea in acid medium which is retained (98.7 ^+- 0.5)% on a cation exchange resin (Dowex 50W-X8, 100 - 200 mesh) while (99.8 ^+- 0.05)% ⁹⁹Mo passes through it, due to the non formation of such complex in the same experimental conditions. The radionuclidic purity of the separated ⁹⁹Mo verified by using gamma spectrometry was found to be suitable for the preparation of ⁹⁹Mo - ⁹⁹ sup (m)Tc generators. The retention of ⁹⁹Mo on an alumina column as function of ph was investigated. the best pH range for this purpose was found to be between 4.0 - 4.5. the ⁹⁹Mo - ^99mTc generator was prepared. the elution of^99mTc was carried out with physiologic saline solution. The radionuclidic purity of the eluate was found suitable and the product can be used for Nuclear Medicine applications. (author)

[en] Thiourea reacts with tellurium-IV ions, in sulfuric medium, to form cationic complex which is strongly retained on cationic ion exchanger. The method was applied to separate ⁹⁹Mo from ¹³²Te obtained in the fission of ²³⁵U since molybdenum does not form such complex and passes throught the cationic exchanger column in the molibdate form. In this paper, the procedure of the tellurium-thiourea complex preparation and its characterization are described. Elemental analysis, ultraviolet and infra-red absorption spectrophotometry as well as thermogravimetry were used to characterize the complex. (author)

[en] The radiopharmaceutical ²⁰¹TlCl is used in Nuclear medicine for myocardial visualization. The solution of ²⁰¹TlCl was prepared using ²⁰¹Tl obtained by irradiating a natural mercury target with protons. This radionuclide was subjected to different quality control processes to verify the purity required for its use in Medicine. Some of these controls concerned the determination of ²⁰⁰Tl, ²⁰¹Tl and ²⁰²Tl; the chemical identification of ²⁰¹Tl⁺¹; the hydrazine concentration, mercury contamination and the presence of phosphate. Furthermore, the biologic distribution in Wistar rats and tests for sterility, pyrogens and for toxicity were carried out. It was verified that the solution obtained was in the form of thallous chloride. This radiopharmaceutical can give a good heart image in animals but due to the contamination of ²⁰¹Tl with ²⁰⁰Tl and ²⁰²Tl its use in human beings is not possible unless enriched ²⁰²Hg is used as target of irradiation. (author)

No abstract available

[en] The use of radioisotopes of high specific activity is of great importance in studies on distributions of radioactive substances in living beings. In countries where only low thermal neutron flux reactors are available the production of ⁶⁴Cu of specific activity is carried out by the Szilard-Chalmers process, which involves the braking of the chemical bondings of the compounds. In this work, experiments were carried out by irradiating the compound bis-[N-benzoil-phenylhydroxylaminate] copper (II) in IEA-R₁ nuclear reactor in a thermal neutron flux of 5x10¹² n/cm². Samples without and with thermal treatment before and/or after irradiation were tested. Samples without pre-heating and with thermal annealing were irradiated for 6,5 h and yields of ⁶⁴Cu of about 3,900 MBq/mg Cu were obtained 21 h after the end of irradiation. The results in this work show the possibility of the preparation of ⁶⁴Cu of high specific activity with that compound by the Szilard-Chalmers process. The faseability of its production will depend on the optimization of the chemical processing and on the preparation of ⁶⁴Cu in a suited form for medical applications. (author)

[en] Published in summary form only

[en] A procedure for preparation of carrier - free fluorine-18 is described. The ¹⁸F is produced by neutron irradiation of lithium carbonate and is separated by passing the dissolved material through a 1000⁰ C calcinated aluminium oxyde column. The yield is about 90%, the tritium content 2%; other radioactive impurities are not found. The radiochemical purity is about 93% and the lithium content of the solution is <0.2 ppm