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Smirnova, I.B.; Dontsova, G.V.; Konstantinova, M.M.; Yanushevskaya, M.I.
The problems of natural and modifyed radiosensitivity1983
The problems of natural and modifyed radiosensitivity1983
AbstractAbstract
[en] Ways of protective effect of serotonine adrenaline, noradrenaline and its synthetic analogue isoppoterenol on cells in vivo and in vitro are discussed. It is shown that the effect results from the organism incorporated effect of the compounds by means of hypoxia conditions creation and direct effect on the cell. This can include the therapeutic effect
Original Title
Issledovanie protivoluchevogo vliyaniya biogennykh monoaminov
Primary Subject
Secondary Subject
Source
AN SSSR, Moscow. Inst. Biologii Razvitiya; AN SSSR, Moscow. Nauchnyj Sovet po Problemam Radiobiologii; p. 198-205; 1983; p. 198-205; Nauka; Moscow (USSR); 14 refs.; 8 tabs.
Record Type
Book
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Konstantinova, M.M.; Minin, A.A.; Nekrasova, I.V.; Dontsova, G.V.; Smirnova, I.B.
The problems of natural and modifyed radiosensitivity1983
The problems of natural and modifyed radiosensitivity1983
AbstractAbstract
[en] Data testifying to the fact that the level of endogenous glutathion determines the value of anoxia protection and makes a considerable contribution to antiradiation effect of sulphur-g containing protectors (MEhAn MPG) are presentedm possible mechanism of endogenous glutatheine participation in radioprotective effect is discussed
Original Title
Rol' ehndogennogo glyutationa v modifikatsii radiochuvstvitel'-- nosti kletok astsitnoj kartsinomy Ehrlikha
Primary Subject
Source
AN SSSR, Moscow. Inst. Biologii Razvitiya; AN SSSR, Moscow. Nauchnyj Sovet po Problemam Radiobiologii; p. 108-114; 1983; p. 108-114; Nauka; Moscow (USSR); 14 refs.; 2 figs.
Record Type
Book
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Original Title
Issledovanie roli tiolov v izmenenii radiochuvstvitel'nosti drobyashchikhsya yaits morskogo ezha
Primary Subject
Source
for English translation see the journal Doklady.
Record Type
Journal Article
Journal
Doklady Akademii Nauk SSSR; v. 203(1); p. 254-256
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Original Title
O korrelyatsii urovnya tiolov v kostnomozgovykh kletkakh s vozrastnymi izmeneniyami radiochuvstvitel'nosti myshej
Primary Subject
Source
For English translation see the journal Radiobiology. Published in summary form only .
Record Type
Journal Article
Journal
Radiobiologiya; v. 14(1); p. 114-116
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Original Title
Issledovanie vliyaniya aminoehtilizotiuroniya i 2-aminotiazolina na uroven' belkovykh tiolov v kletkakh kostnogo mozga myshej
Primary Subject
Source
For English translation see the journal Radiobiology.
Record Type
Journal Article
Journal
Radiobiologiya; v. 14(2); p. 285-287
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] In experiments on mice and bone marrow CFUs a study was made of the radioprotective efficiency of serotonin and adrenaline depending on their concentration. It was shown that in order to protect the body a minimum amount of monoamines is requred; the amount to protect CFUs in vivo is about 5 times greater, and to protect CFUs in vitro, the dose is maximum. The animals are protected by such monoamine concentrations which cannot lessen the affection of CFUs in vivo
Original Title
Issledovanie roli zhiznesposobnykh KOEc kostnogo mozga v vyzhivaemosti obluchennogo organizma
Primary Subject
Secondary Subject
Source
For English translation see the journal Radiobiology (USA).
Record Type
Journal Article
Literature Type
Numerical Data
Journal
Radiobiologiya; ISSN 0033-8192; 
; v. 20(2); p. 212-216
; v. 20(2); p. 212-216
Country of publication
ADRENAL HORMONES, AMINES, ANIMAL CELLS, ANIMALS, AZOLES, BIOLOGICAL EFFECTS, CONNECTIVE TISSUE CELLS, DATA, DATA FORMS, DRUGS, ELECTROMAGNETIC RADIATION, EXTERNAL IRRADIATION, HETEROCYCLIC COMPOUNDS, HORMONES, HYDROXY COMPOUNDS, INDOLES, INFORMATION, IONIZING RADIATIONS, IRRADIATION, MAMMALS, NUMERICAL DATA, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PYRROLES, RADIATION EFFECTS, RADIATIONS, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, RODENTS, SOMATIC CELLS, STEROID HORMONES, SYMPATHOMIMETICS, TRYPTAMINES, VERTEBRATES
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] It has been shown on a whole organism (mice) and isolated cells (Ehrlich ascites tumour) that hydroxyurea has a radiosensitizing action and decreases the endogenous thiol content. Amethopterin fails to produce the same effects
Original Title
Issledovanie vliyaniya oksimocheviny i ametopterina na radiochuvstvitel'nost' i uroven' tiolov v biologicheskikh ob''ektakh
Primary Subject
Secondary Subject
Source
For English translation see the journal Radiobiology.
Record Type
Journal Article
Journal
Radiobiologiya; v. 16(4); p. 603-606
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Original Title
Radiochuvstvitel'nost' droyashchikhsya yaits v'yuna v usloviyakh zaderzhki mitoza kolkhitsinom
Primary Subject
Source
For English translation see the journal Radiobiology.
Record Type
Journal Article
Journal
Radiobiologiya; v. 13(3); p. 442-445
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] A single intraperitoneal injection of hydroxyurea (0.5 mg/g) in mice bearing Ehrlich ascites tumour synchronized the growth of tumour cells. The fraction of cells synthesizing (H3-thymidine pulse label) was reduced to less than 10 per cent 30 to 90 min after hydroxyurea administration and reached maximum up to 90 per cent 6-8 hours later. Radioresistance of cells determined by the rate of tumour growth and the number of cells without chromosome aberrations was higher in the population exposed in the S phase. The endogenous thiol content of cellscorrelates well with their radiosensitivity, depending on the growth phase
Original Title
Izuchenie radiorezistentnosti kletok astsitnoj kartsinomy Ehrlikha na stadiyakh G1 i S
Primary Subject
Source
For English translation see the journal Radiobiology.
Record Type
Journal Article
Journal
Radiobiologiya; v. 16(3); p. 373-375
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] It has been found in mice, by a method of splenic exocolonies, that: (1) serotonin, adrenaline and noradrenaline can protect both isolated bone marrow cells and cells in situ (2) a considerable contribution to a radioprotective action of the amines under study on the animal organism is made by their direct protective effect on cells, (3) with serotonin and adrenaline, ''cell'' protection in the organism is added by a radioprotective action of tissue hypoxia caused by these amines
Original Title
O roli neposredstvennoj zashchity kletok krovetvornoj sistemy v protivoluchevom dejstvii nekotorykh biogennykh aminov na zhivotnyj organizm
Primary Subject
Source
For English translation see the journal Radiobiology.
Record Type
Journal Article
Journal
Radiobiologiya; v. 15(5); p. 680-683
Country of publication
ADRENAL HORMONES, AMINES, ANIMALS, AZOLES, DRUGS, HETEROCYCLIC COMPOUNDS, HORMONES, HYDROXY COMPOUNDS, INDOLES, MAMMALS, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PYRROLES, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, RODENTS, STEROID HORMONES, SYMPATHOMIMETICS, TRYPTAMINES, VERTEBRATES
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
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