[en] Objective: To explore the effect of recombinant adenovirus vector mediated mutant IκBα (mIκBα) combined with radiation on the hepatocarcinoma. Methods: Limited dilution method was used to test the virus titer in 293 cells. The HCC9204 cells were infected with MOI 10,20,30 and 50 for 48 h, respectively. The expression of p65 and mIκBα protein was analyzed by Western blot. Transfected HCC9204 cells and controls were treated with 4 Gy γ rays. The inhibition rate of HCC9204 cells was examined by MTT. Rat models of HCC9204 was constructed. AdmIκBα plasmids were injected into tumor tissue and the tumors were administered with 6 Gy γ irradiation 48 hours later. Tumor growth at different time points was recorded during 28 days. Results: The titer of AdmIκBΑ is 1.252 x 10⁹ pfu/ml. The expression of mIκBα protein was increased with titer of AdmIκBα, and p65 protein began to decrease when MOI was 10, and reached the lowest when MOI was 50, they were all dose-dependent. The proliferation of HCC9204 cell lines were suppressed, as was more significant combined with radiation, and the effect was in a viral dose-dependent manner. From days 7 to 28 after AdmIκBα gene and radiotherapy, the tumor growth was significantly slower than after irradiation or gene therapy alone. Conclusions: Recombinant adenoviral-mediated mIκBα gene, combined with irradiation, can increase the cell-killing effect. It is better than that of either one alone. (authors)

[en] Highlights: • Cu₂O nanospecies anchored on/within mesoporous TiO₂ forming hybrid photocatalyst. • Oxygen vacancy stimulated Z-scheme mechanism inhibits photo corrosion of Cu₂O. • High activity and stability for hydrogen production in both water and seawater. • Strong coupling between Cu₂O and TiO₂ extends visible light absorption and charge separation. -- Abstract: Oxygen vacancy stimulated direct Z-scheme Cu₂O/TiO₂ hybrid photocatalysts were designed and constructed through a Cu²⁺ ions adsorption-reduction strategy with Cu₂O nanospecies decorated on/within mesoporous TiO₂ microspheres. Narrow band gap of Cu₂O favors visible light absorption. The mesoporous structure stabilizes Cu₂O nanospecies and benefits the efficient charge carrier mobility and light harvest. The high specific surface area provides more photocatalytic active sites for both Cu₂O and TiO₂ components. Oxygen vacancy stimulated all-solid direct Z-scheme electron transport mechanism was proposed to explain the high activity and stability of the hybrid catalyst. The catalyst behaves enhanced hydrogen evolution rate of 11 mmol h⁻¹ g⁻¹ in water and 5.1 mmol h⁻¹ g⁻¹ in seawater, respectively. The highest AQY of hydrogen production is 15.1% in water (and 8.4% in seawater) at 365 nm. The work will provide new insight for controllable creation of Z-scheme photocatalysts for practical hydrogen evolution from water and seawater splitting.

[en] CdS nanowires with typical length more than 8 μm and width of 30 nm on average have been successfully synthesized through Cd(NO₃)₂ reacting with CS₂ and ethylenediamine in microemulsion system of sodium dodecylbenzene sulfonate (SBDS). The microstructures of the as-synthesized CdS nanowires were characterized using XRD, transmission electron microscopy (TEM) and HRTEM. The possible formation mechanism was discussed. The morphologies of CdS sample strongly depend on the concentration of surfactant in solutions

[en] Highlights: : • One-step synthesis of N-doped carbon quantum dots hybridized NiFe-LDH of 1.4 nm thickness. • The BET surface area of the products was 226.7 m² g⁻¹. • The overpotential is 363 mV at large current density of 500 mA cm⁻². • NCD@NiFe-LDH shows excellent durability and stability at 1000 mA cm⁻². -- Abstract: : Herein, we have developed a one-step ionothermal accompanied thermolysis strategy based on metal chloride deep eutectic solvent (DES) precursors to synthesize NiFe layered double-hydroxide ultrathin nanosheets hybridized with N-doped carbon quantum dots (NCD@NiFe-LDH). The NCD@NiFe-LDH hybrid shows hierarchical three-dimensional flower-like morphology assembled with ~1.4 nm ultrathin nanosheets possessing higher surface area values and well conductivity. The as-synthesized NCD@NiFe-LDH hybrid exhibits excellent performance for oxygen evolution reaction (OER) and just require 363 mV to achieve a higher current density of 500 mA cm⁻² compared to the state-of-the-art IrO₂ in 0.1M KOH. Besides, NCD@NiFe-LDH hybrid shows long-term stability and satisfactory durability even at 1000 mA cm⁻². Such an excellent OER performance at high current density can be ascribed to the unique porous ultrathin structure with abundant active edges and sites and the synergistic effect of the NCD and NiFe-LDH. The work offers a new way for the design and synthesis of other carbon-hybridized LDH ultrathin nanosheets with unique electrochemical properties.

[en] PANI/CeO₂/Ni(OH)₂ hierarchical hybrid spheres were successfully prepared by a simple one-step self-assemble reaction. The structure and morphology characterization revealed the hybrid spheres were constructed with self-assembled nanosheets. The formation mechanism of the hierarchical structure was discussed. N₂ adsorption–desorption isotherms showed that the PANI/CeO₂/Ni(OH)₂ had improved specific surface area. Under optimized conditions, the PANI/CeO₂/Ni(OH)₂ hierarchical hybrid spheres showed highly electrochemical activity and supercapacitor performance compared with Ni(OH)₂ and CeO₂/Ni(OH)₂. The max specific capacitance reached to 2556 F g⁻¹. It was still as high as 2130 F g⁻¹ even at the high current density, showing good rate capability. After 1000 cycles continuous charge–discharge process, the hybrid sphere can retain 95.9% of its initial capacitance, indicating good cycle stability. The asymmetric specific capacitance can be of 348 F g⁻¹ and the capacity retention rate can hold 80.4% after 8000 cycles. Such high performance of PANI/CeO₂/Ni(OH)₂ hybrids may have potential practical application value used in supercapacitors.