[en] The radial distribution of BATAN CS-30 cyclotron magnetic field has been observed and measured. The observation is perfomed in order to determine wether the magnetic field distribution meets the relativistic distribution that will maitain the stability od accelerated particle orbit. The measured values from innermost radius to the outhermost radius were compared to the theoritical calculated values for proton. it was found that the magnetic field radial distribution did not fully agreed with the relativistic distribution. The maximum phase difference accumulation of moving proton and electrode potential was found to be 66.3 degrees. However, it was considered that it should not cause decleration effect on particle. (authors). 4 refs.; 3 figs

[en] Toluidine blue labelled with radioiodine has been used for cholescintigraphy. The labelling of toluidine blue with radioiodine (¹³¹I) by means of reaction at room temperature is presented here. The use of iodide-iodate system in an acidic solvent (0.1 N HCl) gives more labelling yield than H₀₂ or iodomonochloride method. It was presumed that the labelling mechanism is an electrophilic substitution which gives two isomers, but the mole ratio of iodide-iodate does not meet the reaction stoichiometrics. Both the starting material and the resulting iodinated compound gave the same absorption in the visible region while chromatographic determination did not separate them. The separation of inorganic iodide was carried out with Dowex 1x8 (Cl^-) 50-100 mesh anion exchange resin in a 3 ml disposable syringe barrel falled to the 1 ml mark. The radiochemical purity was determined by paper chromatography followed by counting and autoradiography. The use of n-butanol-acetic acid-water mixture (60:15:25, v/v) and 28% NH₄OH-water mixture (1:4, v/v) as the eluting solvent gave not more than 2% difference in the result, but the later had some advantages. The yield of 20-24 hours reaction ranged between 80-90% with less than 2.5% of radiochemical impurity. It was observed that inorganic iodide was released during storage, but after 10 days of ordinary storage conditions the radiochemical impurity was not more than 5%. (author)

[en] Evaluation of iodination on the ethyl ester of poppy seed oil fatty acid by NAA method. Poppy seed oil has been known for having unsaturated bonds. Therefore, the addition of iodine is expected to give a poly-iodo organic compound which can be used for roentgenography diagnosis. However, since the oil has a high viscosity which is not suitable for the mentioned purpose it must be changed into its simple ester prior to the iodination. It was observed that there was no significant change in the double bonds of the alkyl chain, and the reaction yield was also satisfactory. A preliminary experiment showed that direct iodination using I₂ on the ethyl ester did not proceed well. Therefore a iodobromination of the ethyl ester was carried out followed by exchange reaction with I₂ in chloroform. The evaluation using NAA method appeared to show that exchange reaction between Br in the iodobrominated compound and I in the I₂ could proceed well. However, determination of the iodine content did not agree with that of the bromine. It might be caused by the instability of the compounds. It was also observed that I₂ liberated from compounds diffused and penetrated the polyethylene material used for sample purse in the neutron activation. (author). 16 refs.; 4 figs

[en] Evaluation of iodination on the ethyl ester of poppy seed oil fatty acid by N.A.A. method. Poppy seed oil has been known for having unsaturated bonds. Therefore, the addition of iodine is expected to give a poly-iodoorganic compound which can be used for roentgenography diagnosis. However, since the oil has a high viscosity which is not suitable for the mentioned purpose, it must be changed into its simple ester prior to the iodination. It was observed that there was no significant change in the double bonds of the alkyl chain, and the reaction yield was also satisfactory. A preliminary experiment showed that direct iodination using I₂ on the ethyl ester did not proceed well. Therefore, a iodobromination of the ethyl ester was carried out followed by exchange reaction with I₂ in chloroform. The evaluation using N.A.A. method appeared to show that exchange reaction between Br in the iodobrominated compound and I in the I₂ could proceed well. However, determination of the iodine content did not agree with that of the bromine. It might be caused by the instability of the compounds. It was also observed that I₂ liberated from the compounds diffused and penetrated the polyethylene material used for sample purse in the neutron activation. (author). 4 figs.; 16 refs

[en] Experiments have been done in the preparation of radioiodinated fats and fatty acids by using triolein and oleic acid. The radioiodination (¹³¹I) had been carried out by the iodomonochloride method and the radiochemical purity was determined by paper chromatography. It has been found that the final products are stable after a fiew days under ordinary storage condition. (author)

[en] In connection with the potential domestic demand especially in the fields of industry and nuclear medicine, the separation of "1"3"7Cs from "2"3"5U fission process waste is to be of interest although its economic value could be a polemic. A preliminary study on the separation of "1"3"7Cs from the "2"3"5U fission process waste generated in the production of "9"9Mo in P.T. BATAN Teknologi, Serpong, was performed through experiments on "1"3"7Cs picking from sample solution of the radioactive fission waste (RFW). The presented study is aimed to gain experimental data supporting utilization of the matrix of silica gel-supported ferrocyanide complex salt for the separation of "1"3"7Cs from RFW. Subsequent step would be the recovery and purification of "1"3"7Cs as part of production technology of "1"3"7Cs. The RFW sample was batch-treated with the matrix of silica gel-supported ferrocyanide complex salt which was synthesized from silica gel, potassium hexacyanoferrate(II) and copper(II) chloride. The binding of radioisotopes in RFW on the matrix was observed by γ-spectrometry of the RFW solution before and during the treatment. The results showed that approximately 85% of "1"3"7Cs could be picked from the RFW sample into the matrix. Less amount of "9"5Zr and "9"5Nb was bound into the matrix. "1"0"3Ru was slightly bound into the matrix whereas "1"4"1"/"1"4"4Ce and "1"2"9"mTe were not. It was observed that by using 0.2 and 0.4 g of matrix for 10 ml of RFW, the amount of matrix influenced the binding quantity of "9"5Zr and "9"5Nb but not that of "1"3"7Cs. (author)

[en] BATAN is planning to establish an accelerator-based laboratory at P3TM Yogyakarta as an effort in the development and use of accelerator technology for improving industrial performance and public welfare. This paper reviews several aspects of cyclotron technology and describes the combination of a linear accelerator - cyclotron system as an alternative to be considered in the planing of the laboratory. The progress of cyclotron technology is discussed covering three generations, i.e. conventional cyclotron, synchrocyclotron and AVF cyclotron generations. The planning should not consider the accelerator application for radioisotope production because it is established in Serpong with the existing negative ion cyclotron. The proposed facility at P3TM may comprise two linear accelerators coupled with a positive ion cyclotron of synchrocyclotron generation. In fact, the attachment of the synchrocyclotron unit is flexible and it can be installed subsequently if the higher energy particle beam, which can not be produced by the linear accelerators, is extremely needed. Some technical aspects related to ion beam application, building construction and infrastructure, human resources, and specification of function test are discussed for additional information in the implementation of the planning. (author)

[en] The ¹⁴C-methyl labelled tryphenylmethylphosphoniumiodide had been synthesized using Ba¹⁴CO₃ as the starting material. The synthesis of this labelled compound covered 4 steps, i.e.: liberation of ¹⁴CO₂ from Ba¹⁴CO₃ followed by reduction of the ¹⁴CO₂ to produce ¹⁴CH₃OH which was than reacted with HI and finally the resulting ¹⁴CH₃I was reacted with triphenylphosphine. Using 5 mmole of Ba¹⁴CO₃ (89,9 MBeq/mmole), the chemical yield obtained was 55% while the radiochemical yield was 40%. The labelled compound produced was chemically as well as rediochemically pure. (author). 5 refs

[en] The ⁹⁹Mo-^99mTc Chromatographic generators is the most popular system to provide ^99mTc medical radioisotope. Radioisotope Production Centre (RPC)- BATAN has routinely produced the generator loaded with ⁹⁹Mo prepared by ²³⁵U fission. By using fission produced ⁹⁹Mo, the resulting ^99mTc is potentially contaminated by other fission products which are difficult to eliminate completely. In order to study the characteristic of the generator and radionuclidic impurity pattern of the ^99mTc eluates, an evaluation of gamma spectrometric determination has been carried out. The bulk solutions of ⁹⁹Mo produced by RPC BATAN (Indonesia), Nordion (Canada) and ARI (Australia) were loaded to generators manufactured between July 1993 to May 1994. The saline-eluate ^99mTc, in a total volume of 10 ml each, was subjected to gamma spectrometric determination. The radiation of ^99mTc was eliminated by lead shield of 0.6913 cm thickness. The ^99mTc yield fluctuation from 28 generators indicated that the characteristics of the generator columns were very good. The ^99mTc eluates were consistently contaminated by ⁹⁹Mo, ¹³¹ I and ¹⁰³ Ru, although the contamination level in all cases did not exceed the maximum permissible levels. The fluctuation of radionuclidic impurities were probably caused by variation in the irradiation parameter or by variation in the ⁹⁹ Mo separation methods. (author), 23 refs, 1 tab, 3 figs

[en] sup(99m)Tc-gluconate complex for renal imaging prepared by labeling of calcium gluconate solution appeared to show some radioactivity accumulated in the liver. For this reason, the use of gluconate complex prepared by tin(2) chloride reduction of sup(99m)TcO₄^- in sodium gluconate solution was investigated. The radiochemical analysis of the separated sup(99m)Tc-Sn-gluconate-(Na) complex was carried out by Whatman 1 paper chromatography using acetone and saline as the mobile phase. The biological distribution test in Swiss mice showed that the sup(99m)Tc-Sn-gluconate(Na) complex was well accumulated in the renal without significant accumulation in the lung or in the liver. Observation on human, both renal pathologically and clinically normal patient, proved that the complex has potential prospect for renal imaging. (author)