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Tomaz, L; Grynberg, S.; Mourao, A.
X Latin American Symposium on Nuclear Physics and Applications. Book of Abstracts2013
X Latin American Symposium on Nuclear Physics and Applications. Book of Abstracts2013
AbstractAbstract
[en] Currently, many kinds of radioactive sources are used in brachytherapy for cancer treatment. The 125I seed used in this work is the model Onco Seed 6711, produced by Oncura, which is ranked among the best options for treating prostate cancer. This source emits gamma photons with average energy of 28 keV and has a half-life of 59.4 days. After the implants, the natural movement of the organ can cause the seeds undergo slight displacements relative to the position originally planned, which can cause changes in dose distribution in the tumor volume. This work seeks to compare the dose distribution in a solid water phantom of two symmetrical, but different arrangements of four seeds. For this study, the phantom was machined to accommodate the seeds and TLD-100 LiF rod type dosimeters. The study, using TLD dosimeters, was conducted up to 4 cm of the settings. In addition, an Ebt Gafchromic radiochromic film was positioned over the two configurations during a period of time enough for 1 Gy deposition on it, to observe possible changes in the shape of the isodose curves. The TLD results showed a difference up to 35.8% of the dose deposited in the center of the configurations and different doses were deposited at distances corresponding to 1 and 2 cm radius from the symmetrical seeds arrangements. After 3 cm radius, the dose discrepancy is no longer significant. Another important point is that despite the configurations are symmetric, different dose values were deposited at symmetrical points. The isodose qualitative curves shown by the films showed a difference in the shape of that curves. Thus, the different positions of the seeds proved decisive in dose deposition and this fact should be taken into consideration in planning treatment
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Universidad de la Republica, Facultad de Ingenieria, Facultad de Ciencias, Montevideo (Uruguay); National Superconducting Cyclotron Laboratory, Michigan, (United States); Thomas Jefferson National Accelerator Facility, Virginia (United States); [187 p.]; Dec 2013; 1 p; 10. Latin American Symposium; Montevideo (Uruguay); 1-6 Dec 2013; Poster contributions
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Miscellaneous
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ALKALI METAL COMPOUNDS, BETA DECAY RADIOISOTOPES, BODY, DAYS LIVING RADIOISOTOPES, DISEASES, DOSEMETERS, ELECTRON CAPTURE RADIOISOTOPES, FLUORIDES, FLUORINE COMPOUNDS, GLANDS, HALIDES, HALOGEN COMPOUNDS, HYDROGEN COMPOUNDS, INTERMEDIATE MASS NUCLEI, INTERNAL CONVERSION RADIOISOTOPES, IODINE ISOTOPES, ISOTOPES, LITHIUM COMPOUNDS, LITHIUM HALIDES, LUMINESCENT DOSEMETERS, MALE GENITALS, MEASURING INSTRUMENTS, MEDICINE, MOCKUP, NUCLEAR MEDICINE, NUCLEI, ODD-EVEN NUCLEI, ORGANS, OXYGEN COMPOUNDS, PHYSICS, RADIOISOTOPES, RADIOLOGY, RADIOTHERAPY, STRUCTURAL MODELS, THERAPY
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