[en] The Upper Colorado River Basin contains appreciable amounts of undeveloped coal, oil shale, and uranium resources, which are important in the national energy demand system. A mathematical model, which simulates the salt and water exchange phase of potential fuel conversions, has been developed, based on a subbasin analysis identifying available mineral and water resources. Potential energy developments are evaluated with respect to the resulting impacts upon both the quantity and salinity of the waters in the Colorado River. Model solutions are generated by use of a multilevel minimum cost linear programming algorithm, minimum cost referring to the cost of developing predetermined levels of energy output. Level one in the model analysis represents an aggregation of subbasins along state boundaries and thereby optimizes energy developments over the five states of the Upper Colorado River Basin. In each of the five second level problems, energy developments over a subbasin division within the respective states are optimized. Development policies which use high salinity waters of the Upper Colorado River enable a net salinity reduction to be realized in the Colorado River at Lee Ferry, Arizona

[en] Moving mirrors have the disturbing aspect that they can produce fluxes of negative energy, but the mirror trajectories required for this in flat space have some unphysical aspects. However, previous work suggests that a slowly moving mirror outside a black hole can also produce such fluxes. The general theory of moving mirrors in curved space is investigated here, and it is shown that the energy flux has the same functional dependence on the trajectory as it has in flat space. Hence all trajectories which radiate negative energy involve the same unphysical aspects. (author)

[en] An enzyme-radioimmunoassay for the measurement of dopamine is described. It is based on the incubation of plasma or urine in the presence of catechol-0-methyltransferase and S-adenosylmethionine. The 0-methylated dopamine metabolite formed (3-0-methyldopamine) was characterized by radioimmunoassay. As little as 0.5 ng of dopamine can be detected. The assay was found to be specific, since no cross-reactivity was noted for several compounds related to dopamine. The enzyme-radioimmunoassay of dopamine was used to determine the concentrations of dopamine in urine and plasma of normal volunteers. In this group, urinary dopamine averaged 182.1 +- 2.2 μg/24 hr, and the plasma concentration 0.211 +- 0.052 ng/ml. However, in children wPth neuroblastoma, there was a several-fold increase over controls in the average urinary and plasma levels of dopamine (8,500 μ/24 hr and 2.3 ng/ml). The assay was also used to monitor blood levels of dopamine following the administration of L-dopa and dopamine to patients with cardiomyopathy

[en] We consider the creation of massless scalar particles by a moving mirror in two-dimensional space-time. The correct form for the Bogoliubov coefficients is given and their high-frequency behavior is investigated. We next consider the energy radiated by the mirror and show that this is related in the expected way to the number of particles produced only if a particular condition on the trajectory is fulfilled. The well-known moving-mirror formula of Fulling and Davies, which gives the radiated energy as a functional of the mirror trajectory, is here rederived from the Bogoliubov transformation, without recourse to regularization. Finally we analyze the response of a particle detector, and solve the paradox of how the detector can respond even when the mirror is radiating no energy