[en] Objective: To study the necessity of dipyridamole stress myocardial SPECT imaging before the operation in patients with dissecting aneurysm of aorta. Methods: 30 patients with diagnosed dissecting aneurysm of aorta were included. All of them underwent dipyridamole stress and rest myocardial SPECT imaging separately before operation with 1∼7 days' interval between two modalities. Two of the patients also underwent coronary angiography. Results: According to the findings in operation, of the 30 patients, 20 belonged under Debackey I and 10 under Debackey III. In the 19 patients with normal SPECT imaging, 18 had successful operations while the remaining one died of acute inferior wall infarction after operation. The mortality was 5.26%. In the 11 patients with abnormal SPECT imaging, 5 had successful operations while 6 died of cardiac insufficiency or low cardiac output syndrome. Of the 6 cases who died right in or after the operation, 5 belonged to Debackey I and 3 had sandwiches torn to the opening of the right coronary artery. Of these 3 patients, 2 had the sandwiches filled with thrombi or atheromatous plaque,the other one belonged to Debackey III accompanied by the formation of aortic atheromatous plaque. The mortality was 54.55%. Conclusions: Dipyridamole stress myocardial SPECT imaging is necessary for prognostication before operation for patients with dissecting aneurysm of aorta, especially for patients belonging to Debackey I

[en] Objective: To observe the value of using Yun Ke (⁹⁹Tc-MDP) to cure muscular rheumatism. Methods: A 10 years old male patient was diagnosed with muscular rheumatism. His symptoms were wandering and muscular pain and tenderness at lumbosacral region, abdomen and double crus. He was given therapy with Yun Ke everyday, intravenous injection of 5 mg for 30 days. Results: After intravenous injection of Yun Ke within 8 to 72 hours, the pain in the left crus, the lumbosacral portion and the right crus was reduced in respective order. Finally, the pain disappeared, and only the abdominal pain remained. Between 6 and 30 days, the area of abdominal pain reduced little by little to the size of 1.0 x 1.0 cm², which was beside the navel. On the 33 rd day after the initial treatment, we injected him in the previous mentioned area with prednisone and the pain disappeared. Conclusion: Yun Ke (⁹⁹Tc-MDP) is a new medicine for the treatment of rheumatism, and we believe muscular rheumatism is a new indication of Yun Ke

[en] Purpose: To evaluate the clinical value of ²⁰¹Tl myocardial imaging with intervention of short-term ISDN infusion in assessing ischemic but viable myocardium in coronary artery diseases. Methods: Dobutamine stress redistribution-ISDN/reinjection ²⁰¹Tl myocardial imaging was performed in 27 patients with coronary artery disease. The rest ²⁰¹Tl imaging was repeated 1∼3 months after revascularization (RV). Results: 27 patients had 98 segments of perfusion defects on the stress imaging. 58 segments were identified as reversible by ISDN/reinjection ²⁰¹Tl imaging, of which 53 segments identified as reversible psot-RV. 40 segments identified as irreversible by ISDN intervention imaging, 36 segments also identified as irreversible post-RV. The predictive accuracy of ISDN intervention imaging was 90.8%. The location of heart scars found during operation in 8 patients were well concordant with the irreversible segments identified by ISDN infusion imaging. Conclusions: Short-term administration of ISDN before reinjection ²⁰¹Tl myocardial imaging had good practical value for detecting viable myocardium and scar formation

[en] Objective: To study the necessity of radionuclide dynamic renal imaging before the operation for the patients with dissecting aneurysm of aorta. Methods: Twenty-five normal subjects (male: female = 16:9, average age 48.32 ± 10.09) and 54 patients with dissecting aneurysm of aorta (male:female 44:10, average age 54.39 ± 11.55) were included in this study. Twenty-four of them belonged to Debackey I and 30 belonged to Debackey III. They were divided into 3 groups according to the situation of renal function and all of the study groups underwent renal scintigraphy. During the study, time of peak (T_p), half clearing time (T_1/2), clear rate of 20 min (CR_20min) were measured. Results: Renal scintigraphy of 25 normal subjects showed: 1) both kidneys appeared 2 min later than abdominal aorta developed; 2) both kidneys were in the normal position, and with normal shape and size; 3) T_p: (2.89 ± 0.76) min, T_1/2:(7.24 ± 1.64) min, CR_20min: (69.87 ± 5.45)%. The scintigraphic results of the 54 patients with dissecting aneurysm of aorta showed: 1) Group 1, both renal developing time and renal function of both kidneys were in the normal range; 2) Group 2, the sizes of two kidneys were obviously different, renal developing time of the abnormal kidney was extended, and the renal function of two kidneys were different from each other; 3) Group 3, the renal developing time and renal function of both kidneys were abnormal, and were significantly different from that in the control group and group 1. Conclusions: The renal artery is easy to be involved leading to low perfusion and renal insufficiency in the case of dissecting aneurysm of aorta belonging to either Debackey I or III. Renal scintigraphy is more sensitive in renal perfusion and function estimation than other noninvasive examinations, and it could demonstrate early involvement of renal vessels and renal function, this situation is of close relationship with the selection of the operation program and the prediction of the prognosis for the patients. In general, radionuclide dynamic renal imaging is necessary for preoperative patient with dissecting aneurysm of aorta

[en] In this article, we perform a theoretical study to understand morphological differences in femtosecond laser induced periodic surface structures on noble metals. Our numerical study thoroughly examines the role of two competing ultrafast processes, electron-phonon energy coupling and hot electron diffusion, following femtosecond laser heating of metals. The calculation results confirm our previous experimental work on femtosecond laser induced periodic surface structures on noble metals, where electron-phonon coupling strength is believed to play the dominant role

[en] We proposed a quantitative method to detect atomic position in atomic intensity images from experiments such as high-resolution transmission electron microscopy, atomic force microscopy, and simulation such as phase field crystal modeling. The evaluation of detection accuracy proves the excellent performance of the method. This method provides a chance to precisely determine atomic interactions based on the detected atomic positions from the atomic intensity image, and hence to investigate the related physical, chemical and electrical properties. - Highlights: • A simple method is proposed to precisely detect the atomic position in atomic intensity images. • The detection accuracy is pretty high by using all the intensity information. • Analyses of intrinsic static atomic interactions and atomic dynamics are presented

[en] Objective: To study the biological properties of a new myocardial perfusion imaging agent [⁹⁹Tc^m(CO)₃(MIBI)₃]⁺ in animal and to compare it with ⁹⁹Tc^m-methoxyisobutylisonitrile (MIBI). Methods: Solution of [⁹⁹Tc^m(CO)₃(MIBI)₃]⁺ for intravenous injection was prepared. The radiochemical purity was 85% and labeling percentage was over 90%. Three dogs were involved, the dose of [⁹⁹Tc^m(CO)₃(MIBI)₃]⁺ for each dog was 555 MBq at each time of experiment. The pharmacokinetics, biodistribution, ratio of T/NT and myocardial imaging were investigated. Results: The pharmacokinetics of [⁹⁹Tc^m(CO)₃(MIBI)₃]⁺ conformed to two-compartment model, T(α)_1/2=(1.33 +- 0.12) min. T(β)_1/2=(102.33 +- 25.58) min, CL=(401.33 +- 73.51) mL/h. The time-radioactivity curves showed that the liver uptake curves of [⁹⁹Tc^m(CO)₃(MIBI)₃]⁺ were below the myocardial curves, while that of ⁹⁹Tc^m-MIBI were above the myocardial curves. The myocardial uptake %ID at 10, 30, 60, 90 and 120 min, and heart to lung and heart to liver activity ratio of the new agent were higher compared with ⁹⁹Tc^m-MIBI. The planar and SPECT images of [⁹⁹Tc^m(CO)₃(MIBI)₃]⁺ during 10 to 120 min showed with good quality with lower lung and liver radioactivities. Conclusion: The results show that the [⁹⁹Tc^m(CO)₃(MIBI)₃]⁺ is better than ⁹⁹Tc^m-MIBI in myocardial imaging and warrant further investigation as a potential myocardial perfusion imaging agent

[en] Using computers to inspect the nuclear reactor fuel-changed system is helpful for the improvement of the security and reliability of the refueling operation. Nuclear reactor refueling supervision system is developed with the configuration software. Because the system is very complex and a great deal of data should be recorded, it requires a powerful database to suport. This paper analyzes the dat ato be recorded and introduces the solution for real-time recording. (authors)

[en] Objective: To study the biological properties of the myocardial imaging agent ⁹⁹Tc^mN(NOEt)₂ and compare its redistribution characters with ²⁰¹Tl. Methods: The ⁹⁹Tc^mN(NOEt)₂ was prepared. Blood clearance, biodistribution, imaging and redistribution imaging with ⁹⁹Tc^mN(NOEt)₂ or ²⁰¹Tl were studied in 5 dogs. Results: Radiochemical purity of ⁹⁹Tc^mN(NOEt)₂ was (98.41 +- 0.46)%, blood clearance T(α)_1/2(2.8 +- 0.1) min, T(β_1/2 = (142.7 +- 32.7) min, Cl = (292.3 +- 117.1) mL/h. Imaging studies demonstrated that ⁹⁹Tc^mN(NOEt)₂ was distributed rapidly in the myocardium of the dogs, disappearance of pulmonary uptake was faster than that of myocardial uptake, the uptake was higher in liver. At 10, 30, 60, 90 and 120 min after injection the myocardial uptakes were (4.27 +- 0.21), (5.3 +- 1.48), (5.3 +- 0.66), (4.0 +- 0.53) and (3.67 +- 0.35)% ID; the heart-to-lung ratios and the heart-to-liver ratios of these time points were 1.24 +- 0.31, 2.03 +- 0.45, 2.33 +- 0.31, 2.23 +- 0.5, 2.07 +- 0.49, 0.94 +- 0.08, 0.78 +- 0.15, 0.56 +- 0.22, 0.53 +- 0.22, 0.38 +- 0.15, respectively, the myocardial images were most distinct at 30 and 60 min postinjection. The results of redistribution in ischemic myocardium of dogs with ⁹⁹Tc^mN(NOEt)₂ or ²⁰¹Tl were about the same. Conclusion: ⁹⁹Tc^mN(NOEt)₂ is very worth to be one of the new myocardial imaging agents, it has the re-distributive character just as that of ²⁰¹Tl

[en] Objective: To investigate the role of lung perfusion imaging in evaluating thrombolysis therapy in patients with pulmonary embolism. Methods: 47 patients (Males: Female = 27:20) aged 19-81 years (mean 52.8 years), were classified into 3 groups according to their courses of the disease: Group 1: less than 1 week (n = 17); Group 2: between 1 to 2 weeks or longer than 1 month with the symptoms reoccurred or deteriorated within recent 2 weeks (n 16); Group 3: longer than 1 month without symptoms reoccurred in recent 1-2 weeks (n = 12). In addition, there were 2 cases had the disease for between 2 weeks to 1 month. Lung perfusion imaging was performed on all cases before thrombolysis, 5-10 days after thrombolysis and 2-4 weeks after continuous anti-coagulative therapy. Also, it was performed on 8 cases who had had one course of thrombolysis and then 6-18 months' oral anti-coagulative therapy. Results: Lung perfusion was improved by 75.5% in Group 1, 74.3% in Group 2 and 5.3% in Group 3. The differences between Group 3 and Group 1,2 were significant (P < 0.001). It was further improved in 87.5% in patients given long-term anti-coagulative therapy. Conclusions: Lung perfusion imaging is valuable for efficacy evaluation of thrombolysis. As to patients with the disease course less than 2 weeks, the efficacy of thrombolysis can be high up to 74.9%. Thrombolysis combined with anti-coagulative therapy are effective to some extent for pulmonary embolism with the course more than 2 weeks or 1 month, and the patients should be actively treated so as to improve the prognosis for more patients with pulmonary embolism. Moreover, long-term oral anticoagulant using may be helpful for some cases