[en] This book on tumours and tumourous diseases comprises two parts: 1. Bone tumours and tumourous lesions. 2. Soft tissue tumours and tumourous lesions. Details are presented on pathology, diagnosis, conservative and perioperative therapy, surgical therapy, complications after resection, indicators for amputation, recommendations for follow-up treatment, radiotherapy, radionuclide therapy, alternative therapies, therapy concepts in case of metastases, tissue engineering and plastic surgery. (uke)
[de]
Der vorliegende Band der Reihe Orthopaedie und orthopaedische Chirurgie behandelt das Thema Tumoren und tumoraehnliche Erkrankungen. Der Band teilt sich in zwei Kapitel: 1. Knochentumoren und tumorartige Laesionen und 2. Weichteiltumoren und tumorartige Laesionen. Dargestellt werden Pathologie, Diagnostik, konservative und perioperative Therapie, chirurgische Therapie, Komplikationen nach Resektion, Indikatoren zur Amputation, Nachsorgeempfehlung, Strahlentherapie, Radionuklidtherapie, alternative Therapieverfahren, Therapiekonzepte bei Metastasen, Tissue Engineering und plastisch-chirurgische Massnahmen. (uke)Source
Orthopaedie und Orthopaedische Chirurgie; 2005; 400 p; Thieme; Stuttgart (Germany); ISBN 3-13-126181-1; 
[en] The authors describe a series of 18 patients with an intrasellar mass incidentally discovered by computed tomography or magnetic resonance imaging. The average size of the mass was 13 mm, with a range from 5 to 25 mm. Initial ophthalmologic examination revealed bitemporal hemianopia in 2 patients. Results of routine endocrine testing showed partial hypopituitarism in 5 patients and growth hormone hypersecretion without signs and symptoms of acromegaly in 1 patient. Four patients underwent neurosurgery. Histologically, one chondroid chordoma and three pituitary adenomas were found. In the remaining 14 patients treated conservatively, repeated computed tomography and magnetic resonance imaging revealed no significant change in tumor size at the time of follow-up. The results suggest that the incidentaloma of the pituitary gland is a benign condition that does not necessarily require neurosurgical intervention
Journal
JAMA, Journal of the American Medical Association; ISSN 0098-7484; ; CODEN JAMAA; v. 263(20); p. 2772-2776
; CODEN JAMAA; v. 263(20); p. 2772-2776
[en] Purpose: In the present study the reduction of artifacts using an extended CT scale technique was examined in 5 vitallium and 5 titanium-aluminium-vanadium tumor prostheses. Methods: 5 titanium-aluminium-vanadium and 5 vitallium distal femur Mutars trademark tumor prostheses (Mutars trademark - Modular Universal Tumor And Revision System) were implanted in 10 human femur specimens. 110 artifical drill hole lesions of 1 mm, 2 mm, 3 mm, 5 mm and 8 mm diameter were placed in the bone around the hexagonal stem of the tumor prosthesis and furthermore in the proximal part of the femur. All specimens were examined using conventional CT and an extended CT scale technique in a slice thickness of 3 mm. Results: In the proximal part of the femur all drill holes could be detected using 3 mm slices, no artefacts were observed. Along the hexagonal stem smooth lines arising from each hexagonal plane could be observed. This made it impossible to detect a 1 mm drill in 1 vitallium and in 1 titanium-aluminium-vanadium stem. There was no difference between the extended CT scale and conventional CT. Conclusion: The extended CT scale did not significantly (p > 0.05, t-test) improve the imaging of artifical drill hole lesions along the hexagonal Mutras trademark stem. (orig.)
[de]
Zielsetzung: Diese experimentelle Studie untersucht die Moeglichkeit der Artefaktreduktion bei Tumorprothesen durch Verwendung der extended-field CT-Technik. Methode: In 10 anatomischen Praeparaten wurde jeweils ein Mutars trademark -Tumorendoprothesenschaft (Mutars trademark - modular universal tumor and revision system) in zementfreier Technik in die Femurdiaphyse implantiert (5 Kobalt-Chrom-Molybdaen-Schaefte, 5 Titan-Aluminium-Vanadium-Schaefte). Insgesamt wurden 110 Bohrungen mit unterschiedlichen Durchmessern (1, 2, 3, 5 und 8 mm) entlang der intramedullaeren Schaefte sowie proximal der Schaefte in den kortikalen Knochen eingebracht. Alle anatomischen Praeparate wurden in herkoemmlicher Technik und mit der extended-field CT-Technik mit einer Schichtdicke von 3 mm untersucht. Ergebnisse: Proximal des Prothesenschaftes liessen sich saemtliche Bohrungen darstellen. Entlang des hexagonalen Prothesenschaftes trat in allen Faellen ein feines, regelmaessiges Artefaktmuster auf. Dies machte die Abgrenzung der 1 mm durchmessenden Bohrloecher bei einem Kobalt-Chrom-Molybdaen-Schaft und einem Titan-Aluminium-Vanadium-Schaft unmoeglich. Ein signifikanter Unterschied der Artefaktreduktion zwischen der herkoemmlichen Technik und der extended-field CT-Technik war bei dem verwendeten Implantat nicht festzustellen (p > 0,05; t-test). Schlussfolgerung: Die extended-field CT-Technik zeigte bei dem verwendeten hexagonalen Schaftsystem keinen Vorteil im Vergleich zur herkoemmlichen CT. (orig.)Journal
RoeFo - Fortschritte auf dem Gebiete der Roentgenstrahlen und der Bildgebenden Verfahren; ISSN 1438-9029; ; v. 173(12); p. 1099-1103
; v. 173(12); p. 1099-1103
[en] The experience with bilateral simultaneous inferior petrosal sinus catheterization and determination of the ACTH-concentration in 21 patients is reported. Venous blood sampling in the right and left inferior petrosal sinus was obtained before and after stimulation with Corticotropin-Releasing-Hormone (CRH). In 13 patients with Cushing's Syndrome a ACTH gradient (central versus peripheral) was measured. In all patients who were operated (11/13) a microadenoma was confirmed. In all patients with a central/peripheral gradient of the ACTH-levels at the same time an ipsi versus contralateral gradient between the two sides could be established after administration of CRH, which allowed a correct localization of the microadenoma. In 11 of 13 patients the site of the microadenoma was confirmed intraoperatively. (orig.)
[de]
Es wird ueber die Erfahrungen mit 21 Patienten mit Morbus Cushing oder Cushing-Syndrom berichtet, bei denen eine bilaterale, simultane Katheterisierung des Sinus petrosus inferior zur ACTH-Bestimmung vor und nach Gabe von Corticotropin-Releasing-Hormon (CRH) durchgefuehrt wurde. Bei 13 Patienten konnte ein zentral/peripherer ACTH-Gradient nachgewiesen werden. Das vermutete Mikroadenom wurde bei allen bisher operierten Patienten (11/13) bestaetigt, und die Patienten wurden geheilt. Gleichzeitig gelang es aufgrund der Seitendifferenz der ACTH-Werte, das Mikroadenom zu lokalisieren. Bei allen Faellen bestaetigte sich operativ die korrekte Seitenlokalisation. (orig.)Journal
RoeFo - Fortschritte auf dem Gebiete der Roentgenstrahlen und der Nuklearmedizin; ISSN 0340-1618; ; CODEN RFGND; v. 148(3); p. 275-278
; CODEN RFGND; v. 148(3); p. 275-278
[en] We treated a patient with large multiple chondrosarcomas derived from multiple cartilaginous exostoses. One sarcoma originated in the left pubic bone and the other sarcoma in the posterior aspect of the greater trochanter of the left femur. Thirty months after hindquarter amputation, the patient is alive without relapse. This is the first report of a patient with synchronous multiple malignant transformation of multiple cartilaginous exostoses. (orig.)
Journal
[en] The only curative approach for osteoid osteoma is operative removal of the nidus, but intraoperative detection of the nidus is difficult even when an X-ray amplifier is used. A simple probe-guided operative procedure using technetium-99m methylene diphosphonate is described, and the results and follow-up in 12 patients are reported. In addition physical properties of the probe have been evaluated by phantom measurements. (orig.)
Journal