[en] Objective: To compare the short-term and long-term therapeutic response of uterine artery chemoembolization with internal iliac anterior trunk arterial chemotherapy performed before radical hysterectomy in patients with stages I b2-II a cervical cancer. Methods: One hundred and fifty-one patients with stages I b2-II a cervical cancer were treated with preoperative intra-arterial chemotherapy before radical hysterectomy was carried out. Patients in study group (n = 113) received uterine artery chemoembolization (UACE), while patients control group(n = 38) received internal iliac anterior trunk arterial chemotherapy. Radical hysterectomy was carried out in all patients within 2-4 weeks after UACE or chemotherapy. The tumor size was measured before and after the procedure,and the survival rate at 2 and 5 years after treatment was calculated. Results: The mean maximum diameter of the tumors was (4.58 ± 0.37) cm before interventional therapy, and it was (2.11 ± 0.24) cm in two weeks after interventional therapy. The complete response rate of study group and control group was 31.9% and 21.1% respectively. The total effective rate of study group and control group was 94.7% (107/113) and 76.3% (29/38) respectively. The effective rate of study group two weeks after therapy was significantly higher than that of control group. No surgical margin infiltration was observed in both groups. Pathological findings in study group included vascular invasion around surgical margin (n = 3), parametrial invasion (n = 5) and pelvic lymph node metastasis (n = 6), while in control group vascular invasion around surgical margin, parametrial invasion and pelvic lymph node metastasis were found in one, two and one cases respectively. The two-year and five-year survival rate in study group were 80.9% (68/84) and 73.4% (47/64) respectively, while the two-year and five-year survival rate in control group were 81.3% (26/32) and 75.0% (18/24) respectively. No significant difference in survival rate existed between two groups. Conclusion: Uterine artery chemoembolization can markedly reduce the volume of cervical cancer,which is very helpful for surgical resection. The therapeutic effectiveness of UACE is superior to internal iliac anterior trunk arterial chemotherapy, therefore, UACE should be regarded as neo-adjuvant intra-arterial chemotherapy of first choice for patients with stages I b2-II a cervical cancer. (authors)

[en] Objective: To evaluate the clinical efficacy of selective salpingography (SSG) and fallopian tube recanalization (FTR) in diagnosing and treating fallopian tubal infertility. Methods: SSG was performed in 459 patients and a total of 895 fallopian tubes were proved to be completely or incompletely occluded. Under fluoroscopic guidance, a catheter was managed to be placed in the tubal ostium, then a catheter and guide wire system was used to clear the proximal tube. The cumulative pregnancy rate within eighteen months after the treatment was calculated, and the postoperative tubal patency degree was compared with the preoperative one. Results: After FTR complete patency was achieved in 572 tubes(63.9%). For complete occluded tubes the postoperative patent rate was 80.3%(53/66), while it was 96.7% (802/829) for incomplete occluded tubes. During the follow-up period of 18 months, the pregnancy was confirmed in 43.9% patients(93/212), among which ectopic pregnancy was seen in 2.1% patients (2/93). The median procedure-conception interval was 8.2 months. The pregnancy rate was 51.3% (58/113) in patients with basically patent bilateral fallopian tubes, and it was 35.4% (35/99) in patients with incomplete patent fallopian tubes. Conclusion: The results clearly indicate that SSG together with FTR is a safe and effective method for the treatment of female infertility caused by proximal blockage or incomplete occlusion of the fallopian tubes. (authors)