[en] Six kinds of diamino-dithiol compounds are labelled with ⁹⁹Tc^m by ligands exchange reaction. Their ligands exchange percentage is over 95%. The biodistribution of one of these compounds in mice shows 0.88% brain uptake after two minutes and 0.28% after 15 minutes respectively. Although the brain uptake is lower for this compound, it has longer retention in brain. So, the experiment results are valuable to the design of new brain imaging agent in the future

[en] Several thymidine analogues substituted with closo- and nido-carborane at the N-3 position were synthesized. The nido-carboranyl thymidine analogues were designed to be effective substrates for human thymidine kinase 1 in combination with an increased water solubility sufficient for clinical application in boron neutron capture therapy. This was done because N-3 substituted closo-carboranyl thymidine analogues previously synthesized in our laboratories were good TK1 substrates but were poorly water-soluble. Newly synthesized zwitterionic amino nido- and the corresponding neutral closo-m-carboranyl thymidine analogues exhibited excellent TK1 phosphorylation rates up to 75% relative to thymidine, indicating that these compounds were good substrates for thymidine kinase 1. Thin layer chromatographic studies were indicative of increased hydrophilicity of the synthesized nido-carboranyl thymidine analogues compared with their closo-carboranyl counterparts and previously reported closo-carboranyl thymidine analogues

[en] For preparation of 3-(2-phenyl-2-cyclopentyl-2-hydroxyethoxy) [3-³H] quinuclidine, firstly [3-³H]quinuclidol is prepared by catalytic tritiation of quinuclidone with PtO₂. Then from the reaction of [3-³H] quinuclidol and 1-phenyl-1-cyclopentyl-cyclo ethane, the target product can be obtained. The specific activity is 740 TBq/mol, and the radiochemical purity is over 95%

[en] Relatively little is known about the effects of regional warming on the carbon cycle of subtropical evergreen forest ecosystems, which are characterized by year-round growing season and cold winters. We investigated the carbon balance in three typical East Asia subtropical evergreen forests, using eddy flux, soil respiration and leaf-level measurements. Subtropical evergreen forests maintain continuous, high rates of photosynthetic activity, even during winter cold periods. Warm summers enhance photosynthetic rates in a limited way, because overall ecosystem productivity is primarily restrained by radiation levels during the warm period. Conversely, warm climates significantly enhance the respiratory carbon efflux. The finding of lower sensitivity of photosynthesis relative to that of respiration suggests that increased temperature will weaken the carbon-sink strength of East Asia subtropical evergreen forests. (letter)

[en] Climate models simulating continental scale deforestation suggest a warming effect of land clearing on the surface air temperature in the tropical zone and a cooling effect in the boreal zone due to different control of biogeochemical and biophysical processes. Ongoing land-use/cover changes mostly occur at local scales (hectares), and it is not clear whether the local-scale deforestation will generate temperature patterns consistent with the climate model results. Here we paired 40 and 12 flux sites with nearby weather stations in North and South America and in Eastern Asia, respectively, and quantified the temperature difference between these paired sites. Our goal was to investigate the response of the surface air temperature to local-scale (hectares) land clearing across latitudes using the surface weather stations as proxies for localized land clearing. The results show that north of 10°N, the annual mean temperature difference (open land minus forest) decreases with increasing latitude, but the temperature difference shrinks with latitude at a faster rate in the Americas [−0.079 (±0.010) °C per degree] than in Asia [−0.046 (±0.011) °C per degree]. Regression of the combined data suggests a transitional latitude of about 35.5°N that demarks deforestation warming to the south and cooling to the north. The warming in latitudes south of 35°N is associated with increase in the daily maximum temperature, with little change in the daily minimum temperature while the reverse is true in the boreal latitudes. (paper)