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Bergmann, R.; Zessin, J.
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
AbstractAbstract
No abstract available
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Hoff, J. van den; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 109 p; ISSN 1437-322X; ; 2005; p. 37; Available from TIB Hannover: RR 1847(424)
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AMINES, AROMATICS, AUTONOMIC NERVOUS SYSTEM AGENTS, AZAARENES, AZOLES, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, BODY, BRAIN, CARBON ISOTOPES, CENTRAL NERVOUS SYSTEM, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DISTRIBUTION, DRUGS, EMISSION COMPUTED TOMOGRAPHY, EVEN-ODD NUCLEI, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, INDOLES, ISOTOPES, KINETICS, LABELLED COMPOUNDS, LIGHT NUCLEI, MATERIALS, MINUTES LIVING RADIOISOTOPES, NERVOUS SYSTEM, NEUROREGULATORS, NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANS, PYRROLES, RADIOACTIVE MATERIALS, RADIOISOTOPES, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, SYMPATHOMIMETICS, TOMOGRAPHY, TRYPTAMINES
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Zessin, J.; Lipps, B.
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
AbstractAbstract
No abstract available
Primary Subject
Secondary Subject
Source
Hoff, J. van den; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 109 p; ISSN 1437-322X; ; 2005; p. 23-24; Available from TIB Hannover: RR 1847(424)
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Report
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AMINO ACIDS, AUTONOMIC NERVOUS SYSTEM AGENTS, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, CARBOXYLIC ACIDS, CHROMATOGRAPHY, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DRUGS, EMISSION COMPUTED TOMOGRAPHY, EQUIPMENT, EXTRACTION APPARATUSES, FLUORINE ISOTOPES, HOURS LIVING RADIOISOTOPES, HYDROXY ACIDS, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, LIGHT NUCLEI, LIQUID COLUMN CHROMATOGRAPHY, MATERIALS, MINERALS, NANOSECONDS LIVING RADIOISOTOPES, NEUROREGULATORS, NUCLEI, ODD-ODD NUCLEI, ORGANIC ACIDS, ORGANIC COMPOUNDS, OXIDE MINERALS, RADIOACTIVE MATERIALS, RADIOISOTOPES, SEPARATION EQUIPMENT, SEPARATION PROCESSES, SYNTHESIS, TOMOGRAPHY
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Wuest, F.; Zessin, J.
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 20012002
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 20012002
AbstractAbstract
[en] A novel method for a 11C-C bond formation was developed, employing a cross-coupling reaction between a terminal acetylene and [11C]methyl iodide. The method was used for the synthesis of 17α-([11C]prop-1-ynyl)-3-methoxy-3,17β-estadiol. (orig.)
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Johannsen, B.; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 113 p; ISSN 1437-322X; ; Jan 2002; p. 59
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Pawelke, B.; Bergmann, R.; Zessin, J.
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
AbstractAbstract
No abstract available
Primary Subject
Source
Hoff, J. van den; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 109 p; ISSN 1437-322X; ; 2005; p. 36; Available from TIB Hannover: RR 1847(424)
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Report
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AMINES, ANIMALS, AROMATICS, AUTONOMIC NERVOUS SYSTEM AGENTS, AZAARENES, AZOLES, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, CARBON ISOTOPES, CLEARANCE, DISTRIBUTION, DRUGS, EVEN-ODD NUCLEI, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, INDOLES, ISOTOPES, LABELLED COMPOUNDS, LIGHT NUCLEI, MAMMALS, MATERIALS, MINUTES LIVING RADIOISOTOPES, NEUROREGULATORS, NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PYRROLES, RADIOACTIVE MATERIALS, RADIOISOTOPES, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, RODENTS, SYMPATHOMIMETICS, TRYPTAMINES, VERTEBRATES
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Maeding, P.; Fuechtner, F.; Zessin, J.; Wuest, F.
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
AbstractAbstract
No abstract available
Primary Subject
Secondary Subject
Source
Hoff, J. van den; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 109 p; ISSN 1437-322X; ; 2005; p. 28; Available from TIB Hannover: RR 1847(424)
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Report
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ALKALI METAL COMPOUNDS, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, BODY, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DRUGS, EMISSION COMPUTED TOMOGRAPHY, FLUORIDES, FLUORINE COMPOUNDS, FLUORINE ISOTOPES, HALIDES, HALOGEN COMPOUNDS, HOURS LIVING RADIOISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, LIGHT NUCLEI, MATERIALS, NANOSECONDS LIVING RADIOISOTOPES, NUCLEI, ODD-ODD NUCLEI, ORGANS, RADIOACTIVE MATERIALS, RADIOISOTOPES, SODIUM COMPOUNDS, SYNTHESIS, TOMOGRAPHY
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Beuthien-Baumann, B.; Strumpf, A.; Zessin, J.; Bredow, J.; Kotzerke, J.
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
Forschungszentrum Rossendorf, Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual Report 20042005
AbstractAbstract
No abstract available
Primary Subject
Source
Hoff, J. van den; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 109 p; ISSN 1437-322X; ; 2005; p. 9; Available from TIB Hannover: RR 1847(424)
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Report
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AMINO ACIDS, AUTONOMIC NERVOUS SYSTEM AGENTS, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, BODY, CARBOXYLIC ACIDS, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DISEASES, DRUGS, EMISSION COMPUTED TOMOGRAPHY, ENDOCRINE GLANDS, FLUORINE ISOTOPES, GLANDS, HOURS LIVING RADIOISOTOPES, HYDROXY ACIDS, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LIGHT NUCLEI, NANOSECONDS LIVING RADIOISOTOPES, NEOPLASMS, NEUROREGULATORS, NUCLEI, ODD-ODD NUCLEI, ORGANIC ACIDS, ORGANIC COMPOUNDS, ORGANS, RADIOISOTOPES, TOMOGRAPHY, USES
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Evaluation of S-([18F]fluoromethyl)-(+)-McN5652 (FMcN) as a PET tracer for the serotonin transporter
Brust, P.; Zessin, J.; Pawelke, B.; Steinbach, J.
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 20012002
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 20012002
AbstractAbstract
[en] The suitability of FMcN as a PET tracer was studied in six-week-old piglets. The binding equilibrium in piglet brain was reached about 60 min after i.v. administration of FMcN. The binding was significantly reduced by citalopram but not by maprotiline. It was concluded that FMcN may be suitable for use in humans. (orig.)
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Source
Johannsen, B.; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 113 p; ISSN 1437-322X; ; Jan 2002; p. 38
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Report
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AMINES, ANIMALS, AROMATICS, AUTONOMIC NERVOUS SYSTEM AGENTS, AZAARENES, AZOLES, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, BODY, CENTRAL NERVOUS SYSTEM, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DOMESTIC ANIMALS, DRUGS, EMISSION COMPUTED TOMOGRAPHY, FLUORINE ISOTOPES, HETEROCYCLIC COMPOUNDS, HOURS LIVING RADIOISOTOPES, HYDROXY COMPOUNDS, INDOLES, ISOMERIC TRANSITION ISOTOPES, ISOTOPE APPLICATIONS, ISOTOPES, LABELLED COMPOUNDS, LIGHT NUCLEI, MAMMALS, MATERIALS, NANOSECONDS LIVING RADIOISOTOPES, NERVOUS SYSTEM, NEUROREGULATORS, NUCLEI, ODD-ODD NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANS, PYRROLES, RADIOACTIVE MATERIALS, RADIOISOTOPES, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, SYMPATHOMIMETICS, TOMOGRAPHY, TRYPTAMINES, VERTEBRATES
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Zessin, J.; Eskola, O.; Bergman, J.; Solin, O.
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 20012002
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 20012002
AbstractAbstract
[en] A modified procedure for the synthesis of S-[18F-fluoromethyl]-(+)-McN5652 is described. Hydrolysis of the thioester precursor 1 with an aqueous potassium hydroxide solution prevents the formation of a polar side product. Under these conditions the radiochemical yield was increased to 16 ± 4% (corrected for decay and related to starting [18F]fluoride). (orig.)
Primary Subject
Source
Johannsen, B.; Seifert, S. (eds.); Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Bioanorganische und Radiopharmazeutische Chemie; 113 p; ISSN 1437-322X; ; Jan 2002; p. 33
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AbstractAbstract
[en] Aim: characterisation of the influence of different polymeric tube materials of a water target system, used for the production of 18F activity, on the specific activity of radiotracers. Material, methods: target water samples taken from different locations of the 18F water target system of a Cyclone registered 18/9 cyclotron, equipped with Teflon registered (PTFE) or polypropylene (PP) tubes, were analyzed for non-radioactive [19F]fluoride content. [19F]Fluoride content was measured by ion chromatography (IC20, Dinoex) with suppressed conductivity detection. Both the ion chromatographic results and the amount of 18F activity produced were used for the calculation of the specific activity (SA) of [18F]fluoride at the start of the labelling synthesis. To check these results, the SA of the labelled receptor ligand [18F]ZK811460 was also determined by using the different tubing materials. Results: dose-exposed PTFE tubes of the target dispensing (loading) system were identified to be a major source of [19F]fluoride contamination. Conclusion: by replacing PTFE tubes of the target dispensing system with PP tubes, the content of 19F was reduced considerably resulting in an increase of SA of the radiotracer [18F]ZK811460 by factor of two. (orig.)
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Journal Article
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BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, DRUGS, EVEN-EVEN NUCLEI, FLUORINATED ALIPHATIC HYDROCARBONS, FLUORINE ISOTOPES, HALOGENATED ALIPHATIC HYDROCARBONS, HOURS LIVING RADIOISOTOPES, HYDROGEN COMPOUNDS, ISOMERIC TRANSITION ISOTOPES, ISOTOPE APPLICATIONS, ISOTOPES, LABELLED COMPOUNDS, LIGHT NUCLEI, MATERIALS, NANOSECONDS LIVING RADIOISOTOPES, NUCLEI, ODD-EVEN NUCLEI, ODD-ODD NUCLEI, ORGANIC COMPOUNDS, ORGANIC FLUORINE COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANIC POLYMERS, OXYGEN COMPOUNDS, OXYGEN ISOTOPES, POLYETHYLENES, POLYMERS, POLYOLEFINS, RADIOACTIVE MATERIALS, RADIOISOTOPES, SEPARATION PROCESSES, STABLE ISOTOPES
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Preusche, St.; Fuechtner, F.; Steinbach, J.; Zessin, J.; Krug, H.; Neumann, W., E-mail: j.steinbach@fz-rossendorf.de1999
AbstractAbstract
[en] At the Rossendorf PET Centre the PET cyclotron and the radiochemical laboratories are 500 m away from each other. The distance is bridged by a radionuclide transport system (RATS) whose details such as layout, technical parameters, control system and radiation protection are described along with our experience in long-distance transport of radionuclides
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S0969804399001049; Copyright (c) 1999 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)
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