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Daburon, F.; Lefaix, J.L.; Leplat, J.J.; Fayart, G.; Delacroix, D.; Le Thanh, P.
CEA Centre d'Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)1997
CEA Centre d'Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)1997
AbstractAbstract
[en] Non invasive methods of study of the skin blood flow are numerous, but generally do not give any indication on the cutaneous micro-circulatory flow, except for cutaneous laser Doppler. The isotopic exploration of the skin with injected γ radionuclides, even of weak energy, doe snot allow to characterize the skin blood flow, because of the important contribution of the subcutaneous tissues. The use of β emitters energy spectrum, analyzed by different quantitative methods, are proportional to the thickness of the screen localized between the radioactive source and detector. Using simple and complex phantoms composed of tissue equivalent screens, with 32P sources placed at different depths, it was possible to study the degradation of β spectra, simulating respectively the sub-epidermis and sub-dermis vascular levels. A modelization and an experimental study in-vivo are proposed in this work, with 32P phosphate administered intravenously in pigs. (author)
Original Title
Mesure de la circulation sanguine cutanee chez le porc irradie a l'aide de radioisotopes emetteurs β
Primary Subject
Secondary Subject
Source
Jan 1997; 77 p
Record Type
Report
Report Number
Country of publication
ANIMALS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL EFFECTS, BODY, DAYS LIVING RADIOISOTOPES, DECAY, DOMESTIC ANIMALS, EVEN-EVEN NUCLEI, HOURS LIVING RADIOISOTOPES, INTERMEDIATE MASS NUCLEI, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LIGHT NUCLEI, MAMMALS, NUCLEAR DECAY, NUCLEI, ODD-ODD NUCLEI, ORGANS, PHOSPHORUS ISOTOPES, RADIATION EFFECTS, RADIOISOTOPES, STRONTIUM ISOTOPES, VERTEBRATES, YEARS LIVING RADIOISOTOPES, YTTRIUM ISOTOPES
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