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AbstractAbstract
[en] Unscheduled DNA synthesis was induced by UV irradiation of spleen cells obtained from C 57 Bl mice after repeated total body irradiation of 0.05 Gy 60Co (0.00125 Gy/mice) and determined autoradiographically. An enhancement in the ability for repair of UV induced DNA lesions was observed in cells of gamma irradiated animals. While the amount of 3H-thymidine incorporated per cell was increased, the percentage of labeled cells remained unchanged. The present results are compared with previous data on low dose radiation exposure in men. (Author)
[de]
Die unprogrammierte DNA Synthese wurde in den Milzzellen von C 57 Bl Maeusen nach Ganzkoerperbestrahlung mit 0.05 Gy/d 60Co autoradiographisch bestimmt. In den Zellen der gammabestrahlten Tiere konnte eine Zunahme der Faehigkeit zur Reparatur von UV Schaeden der DNA beobachtet werden. Waehrend der 3H-Thymidineinbau pro Zelle signifikant erhoeht war, blieb die Gesamtzahl der markierten Zellen unveraendert. Die vorliegenden Tierexperimente werden mit frueheren Untersuchungen an beruflich strahlenexponierten Personen verglichen. (Autor)Primary Subject
Source
Jul 1983; 15 p; BL--432/83
Record Type
Report
Report Number
Country of publication
ANIMAL CELLS, ANIMALS, AZINES, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL EFFECTS, BIOLOGICAL RADIATION EFFECTS, COBALT ISOTOPES, ELECTROMAGNETIC RADIATION, EXTERNAL IRRADIATION, HETEROCYCLIC COMPOUNDS, HYDROGEN ISOTOPES, INTERMEDIATE MASS NUCLEI, IONIZING RADIATIONS, IRRADIATION, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LIGHT NUCLEI, MAMMALS, MINUTES LIVING RADIOISOTOPES, NUCLEI, NUCLEIC ACIDS, NUCLEOSIDES, NUCLEOTIDES, ODD-EVEN NUCLEI, ODD-ODD NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PYRIMIDINES, RADIATION EFFECTS, RADIATIONS, RADIOISOTOPES, RIBOSIDES, RODENTS, SOMATIC CELLS, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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