Filters
Results 1 - 1 of 1
Results 1 - 1 of 1.
Search took: 0.02 seconds
SINGH, ANUP K.; GUPTA, ALOK; MULCHANDANI, ASHOK; CHEN, WILFRED; BHATIA, RIMPLE B.; SCHOENIGER, JOSEPH S.; ASHLEY, CAROL S.; BRINKER, C. JEFFREY; HANCE, BRADLEY G.; SCHMITT, RANDAL L.; JOHNSON, MARK S.; HARGIS JR. PHILIP J.; SIMONSON, ROBERT J.
Sandia National Labs., Albuquerque, NM (United States); Sandia National Labs., Livermore, CA (United States). Funding organisation: US Department of Energy (United States)2001
Sandia National Labs., Albuquerque, NM (United States); Sandia National Labs., Livermore, CA (United States). Funding organisation: US Department of Energy (United States)2001
AbstractAbstract
[en] This report summarizes the development of sensor particles for remote detection of trace chemical analytes over broad areas, e.g residual trinitrotoluene from buried landmines or other unexploded ordnance (UXO). We also describe the potential of the sensor particle approach for the detection of chemical warfare (CW) agents. The primary goal of this work has been the development of sensor particles that incorporate sample preconcentration, analyte molecular recognition, chemical signal amplification, and fluorescence signal transduction within a ''grain of sand''. Two approaches for particle-based chemical-to-fluorescence signal transduction are described: (1) enzyme-amplified immunoassays using biocompatible inorganic encapsulants, and (2) oxidative quenching of a unique fluorescent polymer by TNT
Primary Subject
Secondary Subject
Source
1 Nov 2001; 23 p; AC04-94AL85000; Available from Sandia National Labs., Albuquerque, NM (US)
Record Type
Report
Report Number
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue