The effect of acute 60Co-gamma-irradiation on the catecholamine level of the tissues in normal and AET-treated rats
AbstractAbstract
[en] The effects of 8 Gy 60Co-irradiation, of AET (280 mg per kg) and of combined treatment on the catecholamine content of the brain, heart and adrenal glands were examined. Irradiation had no effect neither on the noradrenaline- nor on the dopamine content of the brain; the noradrenaline level of the heart decreased during the first 24 hours, followed by a significant increase. In the adrenal glands the adrenaline + noradrenaline content was not influenced, however, the dopamine level increased significantly. AET by itself decreased noradrenaline in the heart and increased dopamine in the adrenal glands. The combined therapy partially prevented the decrease of noradrenaline in the heart, but in other organs it did not influence the effect of irradiation. (L.E.)
Original Title
Akut 60Co-gamma-besugarzas hatasanak vizsgalata normal es AET-vel kezelt patkanyok szoeveti katekolamin-szintjere
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24 refs.
Record Type
Journal Article
Journal
Kiserletes Orvostudomany; ISSN 0023-1878; ; v. 32(1); p. 51-56
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Descriptors (DEC)
ADRENAL HORMONES, AMINES, AMINO ACIDS, ANIMALS, AROMATICS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BODY, CARBONIC ACID DERIVATIVES, CARBOXYLIC ACIDS, CARDIOVASCULAR SYSTEM, CENTRAL NERVOUS SYSTEM, COBALT ISOTOPES, DRUGS, HORMONES, HYDROXY ACIDS, HYDROXY COMPOUNDS, INTERMEDIATE MASS NUCLEI, IRRADIATION, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MAMMALS, MINUTES LIVING RADIOISOTOPES, NERVOUS SYSTEM, NUCLEI, ODD-ODD NUCLEI, ORGANIC ACIDS, ORGANIC COMPOUNDS, ORGANIC SULFUR COMPOUNDS, ORGANS, PHENOLS, POLYPHENOLS, RADIOISOTOPES, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, RODENTS, STEROID HORMONES, SYMPATHOMIMETICS, THIOLS, THIOUREAS, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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