The effect of cadmium and manganese on the distribution of iron-59 in partially-hepatectomized rats
AbstractAbstract
[en] The distribution of iron-59 in blood at various time intervals was studied in sham and partially-hepatectomized rats after a single intravenous injection of 59Fe (III) citrate. A significant difference was observed in the rate of disappearance and reappearance of iron-59 in circulation. Administration of cadmium and manganese at a concentration of 0.5 and 2 mg/kg b. wt., respectively, did not cause any significant change in this pattern. A significant decrease in iron-59 incorporation in the liver of hepatectomized rat was produced by cadmium while manganese had no effect. (author)
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Acta Pharmacologica et Toxicologica; ISSN 0001-6683; ; v. 51 p. 20-23
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