[en] Renal function was investigated in 51 patients after abdominal large field irradiation of different forms. 48% of the patients revealed severe parenchyma degenerations of the left kidney following co-irradiation of the spleen. Equal changes occurred in 16% and 18% of the patients, resp., after sole irradiation of the paraaortic lymph nodes or co-irradiation of the splenic hilum only. Clinical symptoms and resulting consequences are discussed. (author)