AbstractAbstract
[en] Between May 1980 and March 1983, 31 patients with esophageal carcinoma were treated with a high-dose-rate remote controlled afterloading unit, as a boost therapy of the intracavitary irradiation following the external irradiation. The data of these patients were analyzed by the regression analysis which is one of the multivariate analyses, and following results were obtained. 1) Factors which affect local control achieved by intracavitary irradiation were the existence of deep ulcer or stenosis after external irradiation, age of the patient, dosage of intracavitary irradiation and tumor length. 2) The local control estimation index was determined by these five factors. Local control estimation index=1.38950-0.01571 x age+0.04517 x tumor length+0.62167 x stenosis* + 0.94811 x deep ulcer*-0.02969 x dosage of intracavitary irradiation. * Existence of stenosis/ulcer was represented by 1, and absence was represented by 0. 3) The local control estimation indices obtained in the above formula were then approved by applying internal samples, and also external samples. Indices of 0.5 or more mean local failure, and those of less than 0.5 mean possible local control. Examination was then made as to the local control estimation indices of another group of 30 patients who had been treated by external irradiation alone between November 1974 and April 1980. Comparison of the indices of the two groups showed the following results. 1) Rate of possible local control by external irradiation alone was 23%. 2) Rate of possible local control was increased up to 62% by using intracavitary irradiation following external irradiation. (author)
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Nippon Gan Chiryo Gakkai-Shi; ISSN 0021-4671; ; v. 19(7); p. 1425-1431
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