Retention of monodisperse or polydisperse aluminosilicate particles inhaled by dogs - study update
Snipes, M.B.; Boecker, B.B.; McClellan, R.O.
Inhalation Toxicology Research Institute annual report, October 1, 1983-September 30, 19841984
Inhalation Toxicology Research Institute annual report, October 1, 1983-September 30, 19841984
AbstractAbstract
[en] This report updates a study in progress to determine the long-term fate of inhaled 0.7 μm, 1.5 μm, or 2.8 μm activity median aerodynamic diameter (AMAD) or polydisperse (1.5-2.0 μm AMAD) aerosols of 134Cs-labeled aluminosilicate using Beagle dogs. Clearance models developed from results obtained during the first 2 yr after inhalation were used to simulate additional data to 4 yr after exposure. The original models fit the new data satisfactorily, with the exception that the smallest particle size might have an increased dissolution rate at the later times after exposure. These results add to a growing data base on deposition and long-term fate of airborne particles inhaled by a laboratory animal. 2 references, 1 figure
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Source
Guilmette, R.A.; Medinsky, M.A. (eds.); Inhalation Toxicology Research Inst., Albuquerque, NM (USA); p. 73-75; Dec 1984; p. 73-75; Available from NTIS, PC A23/MF A01; 1 as DE85009283
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Report
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Descriptors (DEC)
AEROSOLS, ALUMINIUM COMPOUNDS, ANIMALS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, CESIUM ISOTOPES, COLLOIDS, DATA, DISPERSIONS, DOGS, HOURS LIVING RADIOISOTOPES, INFORMATION, INTAKE, INTERMEDIATE MASS NUCLEI, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MAMMALS, NUCLEI, NUMERICAL DATA, ODD-ODD NUCLEI, OXYGEN COMPOUNDS, RADIOISOTOPES, SILICATES, SILICON COMPOUNDS, SIZE, SOLS, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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