[en] The purpose of this study is to evaluate the performance of immunoscintigraphy (IS) to diagnose hepatic metastases of colorectal carcinoma. PATIENTS: IS was performed in 19 patients because of rising serum titres of the tumor markers (12), to evaluate recurrent carcinoma confirmed by other examinations (6) and to assess the spread of an inoperable rectosigmoid tumor (1). METHOD: F(ab')₂ fragments of anti-CEA and 19.9 monoclonal antibodies were used (1.5 mCi if each). Planar scans of the liver were obtained 3 and 5 days post-injection.sup(99m)Tc sulphur colloid scintigraphy was performed at the same time. The data were compared with ultrasonographic and CT scan findings. RESULTS: In 9 cases, IS showed abnormal foci in the liver region. IS and ultrasonography were used simultaneously in 15 patients. The results agreed 13 times (8 negative, 5 positive); IS was positive twice while the ultrasound scans were negative. IS and CT liver scans were carried out simultaneously in 10 patients. The results agreed in all cases. 5 patients underwent laparotomy. Intraoperative findings agreed with IS data in all cases. Our results emphasize the importance of a painstaking examination of the liver region when using IS to diagnose colorectal tumor recurrence. The agree with those obtained by Deland et al. (Sem Nucl Med 15, 2-11, 1985). (Author)