A new type of discrepancy between cerebral blood flow measured with 133Xe and HmPAO-99Tc perfusion
AbstractAbstract
[en] We report a clinical case of a new type of discrepancy between two tracers usable for brain functional imaging: the Xenon 133 and the HmPAO-99mTc. A 66 year old men had presented a brutal left hemiplegia with transient troubles of consciousness in relation with a right protuberant infarct without hemispheric lesions. The functional studies were performed 4 months after the onset, successively by the Xe inhalation method and immediately after the HmPAO study. On a patient kept still on the camera bed when cerebral blood flow (CBF) study depicted both a right cerebellar low flow and a slightly decreased CBF in the controlateral hemisphere ('hemispheric diaschisis'), the HmPAO SPECT was normal. This observation illustrates both the crossed hemispheric diaschisis and a new type of discrepancy: indeed, the known cases were until now in relation with alterations of the blood: brain barrier, which doses not exist in our report. The explanation of this type of discrepancy remains unclear but is probably linked with the HMPAO retention mechanisms. (author)
Original Title
Discordances entre la mesure du debit sanguin cerebral au xenon 133 et de la perfusion cerebrale au HmPAO 99mTc: un nouveau cas de figure
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Journal Article
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Medecine Nucleaire. Imagerie Fonctionnelle et Metabolique; ISSN 0928-1258; ; CODEN MNIMEX; v. 24(no.6); p. 341-344
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BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BODY, CENTRAL NERVOUS SYSTEM, DAYS LIVING RADIOISOTOPES, EVALUATION, EVEN-ODD NUCLEI, HOURS LIVING RADIOISOTOPES, INTERMEDIATE MASS NUCLEI, INTERNAL CONVERSION RADIOISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPE APPLICATIONS, ISOTOPES, MEDICINE, NERVOUS SYSTEM, NUCLEI, ODD-EVEN NUCLEI, ORGANS, RADIOISOTOPES, TECHNETIUM ISOTOPES, XENON ISOTOPES, YEARS LIVING RADIOISOTOPES
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