[en] A development of RELAP5/CANDU+ code for regulatory audits of accident analysis of CANDU nuclear power plants is on progress. This paper is undertaken in a procedure of a verification and validation for RELAP5/CANDU+ code by analyzing main steam line break accidents of WS 2/3/4. Following the ECC injection in sequence of the steam line breaks, the mismatch in heat transfer between the primary and the secondary systems makes pressure of the primary system instantly peaked to the open setpoint of liquid relief valves. The event sequence follows the result of WS 2/3/4 FSAR, but there is a difference in pressure transient after ECC injection. Sensitivity analysis for main factors dependent on the peak pressure such as control logics of liquid relief valves. ECC flow path and feedwater flow is performed. Because the pressure increase is continued for a long time and its peaking is high, open and close of the liquid relief valves are repeated several times, which is obviously different from those of WS 2/3/4 FSAR. As a result, it is evaluated that conservative modeling for the above variables is required in the analysis