Effect of 18F-FDG dosage alternation on final PET image
AbstractAbstract
[en] Objective: To assess PET reconstructed image effected by different 18F-FDG dosages with quantitative and qualitative analysis. Methods: To perform PET phantom acquisition by routine clinical parameters after filled with different doses of 18F-FDG solution. An identical slice was extracted from reconstructed image for doing following analysis: the hot area standard uptake value (SUV), the ratio of hot area to cold area, the standard deviation on background area, the ratio of true coincidence to random. Results: 296 MBq: The image uniformity was terribly worse, T/R=0.83, other indexes were irregular. 148 MBq: The image presentation looked like the image without attenuation correction, T/R=1.64, other indexes were moderate. 74, 37 and 18.5 MBq: The images were with excellent uniformity, resolution and contrast, the background noise was suitable, all of the quantitative indexes were good. 9.25 and 4.625 MBq: The uniformity and resolution was degraded terribly because of the higher noise and lower information. Conclusion: Combining above results with other considerations, such as radiation exposure, information amount and acquisition time, the authors think the optimal dosage should be 4.625-11.1 MBq/kg
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Chinese Journal of Nuclear Medicine; ISSN 0253-9780; ; v. 22(4); p. 233-234
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ALDEHYDES, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, CARBOHYDRATES, COMPUTERIZED TOMOGRAPHY, CONTROL, DIAGNOSTIC TECHNIQUES, DOSES, DRUGS, EMISSION COMPUTED TOMOGRAPHY, FLUORINE ISOTOPES, HEXOSES, HOURS LIVING RADIOISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, LIGHT NUCLEI, MATERIALS, MONOSACCHARIDES, NANOSECONDS LIVING RADIOISOTOPES, NUCLEI, ODD-ODD NUCLEI, ORGANIC COMPOUNDS, PROCESSING, RADIOACTIVE MATERIALS, RADIOISOTOPES, SACCHARIDES, TOMOGRAPHY
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