[en] Objective: The study was to evaluate DWI for quantifying liver fibrosis. Methods: A total of 12 volunteers, 47 patients who had chronic HBV or HCV hepatitis and underwent liver biopsy [Scheuer score for fibrosis(S) and inflammation(G)] were enrolled in this study. They were scanned using a 1.5 T MR unit with b value of 0,250,500,750, 1000 s/mm². ADCs at b_250-1000 and b_500-1000 were the average ADCs of b=250, 500, 750, 1000 s/mm² and b=500, 750, 1000 s/mm². The studied the correlation between Scbeuer scores and ADC values, and conducted Mann-Whitney U test and Logistic regression to evaluate ADC for prediction of fibrosis scores. Results: The average ADCs were (1.41± 0.11), (1.37 ±0.09), (1.27 ± 0.05), (1.26 ± 0.04), (1.22 ± 0.06) mm²/s respectively from SO to S4, stage at b=750 s/mm² (F=18.31, P<0.01). With the increase of fibrosis score, the average ADC decreased gradually, the two were better negatively correlated at b_250-1000 (r=-0.727, P<0.01) than other b values. Using b₇₅₀ and the two combined b values, the found significantly lower ADCs in S2 or greater versus S1 or less and in S3 or greater versus S2 or less fibrosis (P<0.01). The best predictor for S2 or greater was b₇₅₀ with the largest AUC of 0.909, sensitivity of 85.7%, and specificity of 100.0% (ADC ≤ 1.35 x 10^-3 mm²/s). The best predictor for S3 or greater was b_250-1000 with the largest AUC of 0.864, sensitivity of 69.6%, and specificity of 95.8% (ADC ≤ 1.53 x 10^-3 mm²/s). Conclusion: DWI can be a good predictor for scoring liver fibrosis for S2 or S3 stage above, while b₇₅₀ and the combined b values are suitable for evaluation. (authors)