[en] Full text: The given article talks about how cancer can impact on human organs and how find an optimal and safe methods of treatment of this desease. There were advised radiotherapy that shows a sufficient potential, but unfortunately it is not enough, through its severe damage to health. A new type of in-situ radiation method has been tried using 17Y2O3-19AL2O3-64SIO2 glass microspheres that are preared by a conventional melt quench method. But there was reported a novel method to production of yttrium microspheres by paraffin oil gelation column. In this study three parameters play an important role in gelation time : concentration of Teos, concentration of water and reaction temperature. In the present study a systematic study was carried out by a sol-gel process using a sequential addition method and the results are discussed. The main parameters and their effects on gelation time are discussed. The production of brachytherapy microspheres was studied. Further all this process management described.