[en] Aimed at problems of long term existed low mining efficiency and high cost in production of typical Gaoxi uranium deposit among southern hard rock with low grade of uranium deposit, also by support of the improvement and perfection of low grade uranium deposit hydrometallurgical technique through collection partition of irregular and disperse deposit, high efficient stage deep hole open stoping followed by back-filling method was discussed. Technical measure, technology characteristic, result and experience of the method application were basically summarized. And application prospect in southern Jiangxi low grade uranium deposit was probed. (authors)