Maternal and perinatal outcome in preterm prelabor rupture of membranes
AbstractAbstract
[en] Objectives: To assess frequency of preterm premature rupture of membranes and evaluate maternal and perinatal outcome in pregnancies complicated by preterm premature rupture of membranes (PPROM) in our hospital. Setting: Department of Obstetrics and gynecology Ziauddin hospital which is affiliated with Ziauddin University Period: Three year from 24-January-2013 to 18-December-2016 Study design: This was a prospective cross sectional study. Material and Methods: A total of 62 consecutive singleton pregnancies presenting in labor ward having gestational age between 28 to 36 weeks with complains of leaking per vaginum were included in the study after taking informed verbal consent. Frequency of preterm premature rupture of membranes (PPROM) in our hospital, Feto maternal out-come and leaking to delivery interval were noted. The data were analyzed using SPSS version 22.0 statistical package. Results: The frequency of PPROM was 3.27 percent. The latency period was < 48 hours in 43.5 percent of patients who presented between 34-36 weeks gestation, while none of those who presented at or < 30 weeks delivered in the fi rst 48 hrs. 35.5 percent babies were low birth weight (less than 2.5 kg). In 30.6 percent 5 minute Apgar score of <7 was observed; 34 percent developed RDS and Perinatal mortality was seen in 26 percent of babies. Chorio-amnionitis complicated 6.45 percent of pregnancies Conclusion: Preterm premature rupture of membrane is associated with significant increase in perinatal mortality. Duration of Preterm premature rupture of membrane (PPROM), latency period and Apgar score at 5 minute is related with unfavorable fetal outcome. Increase in latency period is also associated with increased risk of chorio-amnionitis. Using the findings of this study obstetricians and neonatologists would be in a better position to provide advice to PPROM experiencing couples. Further studies related to long term neonatal morbidity need to have sample sizes that are much larger and should cover a larger number of institutions. (author)
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Pakistan Journal of Surgery; ISSN 0258-8552; ; v. 35(1); p. 73-77
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