To study correlation between low risk prostate cancers/intermediate risk prostate cancers/high risk prostate cancers and SUVmax values on 68- Ga PSMA PET CT
AbstractAbstract
[en] The study aims to see the correlation between Standardized Uptake Value (Max) of prostatic lesions in relation with risk stratification of prostate cancers. Initial staging 68-Ga PSMA PET CT scans of 286 patients with prostate cancers (Low Risk- 11, Intermediate Risk- 63, High Risk- 212) were assessed. SUVmax values of the prostatic lesions were noted. Gleason’s score as per the respective histopathological reports available from Electronic Medical Records was recorded. Mean and median SUVmax values of respective categories were obtained. Kruskal Wallis test was applied to the given study data. The mean SUVmax in low risk / intermediate risk / high risk prostate cancers was found to be 15.07, 18.80 and 31.50 respectively. The median SUVmax across the categories was 8.78, 18.45 and 26.06 respectively. The median rank in low risk category was 69.09, in intermediate risk category was 104.95 and high risk category was 158.82. As per Kruskal Wallis test, difference between group SUVmax values across low / intermediate / high risk prostate cancer categories is statistically significant. A positive correlation was found between the SUVmax values of prostatic lesions and the risk category of the patient, a higher median SUVmax value being observed in high risk prostate cancers cases and a lower median SUVmax value being observed in low risk prostate cancer cases. The SUVmax value of prostatic primary lesion can be used as a predictive indicator of the risk category of the individual before a 12 core prostate biopsy. (author)
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Indian Journal of Nuclear Medicine; ISSN 0972-3919; ; v. 37(5,suppl.1); p. S44
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BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, BODY, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DISEASES, DRUGS, ELECTRON CAPTURE RADIOISOTOPES, GALLIUM ISOTOPES, GLANDS, HOURS LIVING RADIOISOTOPES, INTERMEDIATE MASS NUCLEI, ISOTOPES, LABELLED COMPOUNDS, MALE GENITALS, MATERIALS, NEOPLASMS, NUCLEI, ODD-ODD NUCLEI, ORGANS, RADIOACTIVE MATERIALS, RADIOISOTOPES, TOMOGRAPHY
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