[en] A process for treating low radioactive uranium wastewater by ultrasonic combined flocculation and precipitation has been developed and optimized. By using arsenazo III spectrophotometry to detect the mass concentration of uranium ions, the optimal coupling mode of ultrasonic flocculation and the optimal values of pH value, flocculant dosage, and ultrasonic power were obtained through single factor experiments. The conclusion drawn is that the optimal coupling method is to first add flocculants, then treat the solution with ultrasound, and finally stir the solution. The optimal values for each single factor are: the initial pH value of the solution is 9, the dosage of flocculant is 80 mg/L, and the sound energy density is 0.36 W/ml.The Box Behnken response surface experiment was designed using Design-Expert software. After completing the response surface experiment, a regression model for uranium ion removal rate was obtained. The highest uranium ion removal rate under theoretical conditions was obtained by solving the model.The predicted values of uranium ions removal rate of 95.68% was obtained with an acoustic energy density of 0.436 W/ml and a flocculant dosage of 88 mg/L at pH 9.It was observed that the actual experimental data under the same conditions are 95.41% The order of the influence factors of each process parameter on the uranium ion removal rate is: pH > flocculant dosage > ultrasonic power. Among them, there was a significant interaction between ultrasonic power and flocculant dosage. (author)