AbstractAbstract
[en] Purpose: The effectivenes of maintenance treatment with PARP inhibitor olaparib in platinum-sensitive recurrent serous, papillary, high-grade carcinoma of the left adnexais presented. Case report: We describe the case report of a cacer patient who was 43 year sold at thetime of diagnosis. After 36 months, a platinumsensitive relapse of a serous, papillary, high-grade tumor of left adnexawas confirmed. The patient was treated with 2-line palliative chemotherapy paclitaxel, carboplatina (7 cycles) and subsequently treated with maintenance treatmet with olaparib untilnow. The basic diseaseis in complete remission. Conclusion: Olaparib is the first PARP inhibitorisindicated as maintenance therapy in patients with BRCA mutations, with newly diagnosed advanced ovarian cancer and also in patients with platinum-sensitive recurrent ovarian cancer who have achieved a terapeutic response to platinm-based chemotherapy. (author)
Original Title
Efektivita udrziavacej liecby s PARP inhibitorom olaparibom pri platina-senzitivnom rekurentnom karcinome ovaria
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Source
18 refs., 4 fig., 3 tab.
Record Type
Journal Article
Journal
Onkologia (Bratislava); ISSN 1336-8176; ; v. 19(3); p. 224-230
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