[en] Objective: To explore the applying value of the diagnosis of dynamic contrast-enhanced MRI (DCE-MRI), diffusion weighted imaging (DWI) and 3D ¹H-MR spectroscopy (MRS) in prostate cancer (PC). Methods: Thirty-two cases with PC and 64 cases with benign prostatic hyperplasia (BPH) which were confirmed with biopsy-proven, operation and follow-up, and 29 healthy volunteers underwent the examinations of DCE-MRI, DWI and MRS. The signal intensity, ADC value, and Cho/Cit ratio and (Cho + Cr)/Cit ratio were measured respectively on the lesions of PC and BPH, normal prostatic peripheral zone (PZ) and normal prostatic central gland (CG) of DCE-MRI, DWI and MRS. The results were statistically treated with ANOVA. Results: The lesions showed obvious enhancement in the early phase of DCE-MRI and washed out in late phase in 18 of 22 cases with PC, who underwent the examination of DCE-MRI. The enhancement was obvious in early and strengthened gradually, and then went to decrease in late phase after peak value on the lesions in 38 of 40 cases with BPH. The signal intensities from different time and different lesions and tissues were treated statistically and the results showed that there were significant differences (P<0.05) between PZ, PC and BPH in different time except 0 s and 120 s between PC and BPH (P> 0.05). The lesions were shown lower signal intensity on ADC map in 26 cases with PC, who were examined with DWI and the average ADC value was (104.23±26.15) x 10^-5 mm²/s. The average ADC Value of the lesions of 43 cases with BPH was (175.21±64.86) x 10^-5 mm²/s. The statistical analysis showed that there were significant differences between PC, BPH and CG except between PZ and BPH. Average Cho/Cit ratio and average (Cho + Cr)/Cit ratio of the lesions of PC were 2.26±0.91 and 2.85±1.01 respectively in 17 cases with PC, who were performed with MRS. The average Cho/Cit ratio and average (Cho + Cr)/Cit ratio were 0.46±0.23 and 0.57±0.20 respectively in 35 cases with BPH. After the statistical analyzing, the results presented that there were significant differences between PC, BPH and normal prostatic tissues except between PZ and CG. The sensitivity, specificity and accuracy of DCE-MRI, DWI and MRS were all more than 70% in displaying PC. Furthermore, the sensitivity, specificity and accuracy of DCE-MRI, DWI and MRS had increased to 87.50%, 94.74% and 92. 59% respectively with the combining use of this three examination methods. Conclusions: DCE-MRI, DWI and MRS could present the specific findings in the diagnosis of PC. The combining application of the three examination methods will further increase the accurate diagnosis of PC. (authors)