[en] The year 2015 continued to be one of significant change, both in relation to the Agency and the global context within which it operates. As countries around the world plan aggressive nuclear power plant construction programmes, prepare to phase out and decommission plants, or to both build and retire plants simultaneously, issues of economics, waste management, public communication and nuclear safety continue to dominate the global discussion regarding nuclear power. As many countries work to absorb the outcome of the COP21 negotiations at the end of 2015, it is becoming increasingly likely that the future of nuclear power will be determined in great respect by non-traditional suppliers and new entrant countries. As reflected in this year's Annual Report, the NEA completed a significant revision of its management structure, which, it is hoped, will enable it to be more flexible, more efficient and more focused on the issues of greatest concern to its member countries. Our members provided input via the process of developing the new Strategic Plan of the Nuclear Energy Agency: 2017-2022, reaffirming their desire to maintain a sharp focus on nuclear safety as our most important mission area, while also reaffirming the vital importance of the NEA as a leading forum for technology cooperation, economic analysis and scientific investigation. In that respect, the NEA's new role as the institutional home of the International Framework for Nuclear Energy Cooperation (IFNEC) continues the Agency's coverage of complex issues associated with the deployment of new nuclear power plants. The NEA also launched the Nuclear Innovation 2050 initiative in 2015, through which NEA hopes to develop a coordinated international agenda for priority nuclear technology research and development on issues ranging from advanced fuel cycles to improved technology and methods for decommissioning retired plants. In all, 2015 was a year of both continued success for the NEA and a year of transition. As old ways of doing business give way to the realities of constrained resources and increasing diversity of views and direction within NEA's member countries, NEA remains focused on the core activities that make it the premier forum for cooperation among countries with the most developed and experienced nuclear infrastructures. Contents: I. Message from the Director-General; II. Nuclear Power in 2015; III. The Fukushima Daiichi Accident and NEA Follow-up; IV. NEA Activities by Sector: Nuclear Development, Nuclear Safety and Regulation, Human Aspects of Nuclear Safety, Radioactive Waste Management, Radiological Protection, Nuclear Science, Data Bank, Legal Affairs; V. General Information: Information and Communications, Organisational Structure of the NEA, NEA Publications and Brochures Produced in 2015