Kode Chemoinformatics

⚛ Molecule in the spotlight ⚛ In October 2024, the U.S. FDA approved VYALEV™, a major advancement in the treatment of advanced Parkinson's disease. While Vyalev does not directly target the underlying causes of Parkinson's disease, such as the aggregation of alpha-synuclein, it addresses the dopaminergic dysfunction that is central to the disease's motor symptoms. Read the article by our #Chemoinformatician Nedra Mekni, PhD and discover more about the Biopathology and evolution in Treatment for Parkinson's Disease. #drugdesign #chemistry #biotechnology #chemoinformatics #neurodegenerative #neurology

Since its foundation in 2012, Kode has continued to grow organically, developing its business with a clear idea: to create a home for everyone who loves analysing data; a place where they can become the cornerstone for process optimisation in any field. After more than 10 years, working with increasingly large companies and clients, the need arose to take a leap in quality that would ensure the company's solidity, not only the effectiveness of the solutions offered. Meeting with EBWorld opened up the prospect of a long-term collaboration with great opportunities, not only commercially but, above all, for the joint growth of our mission. Our CEO Marco Calderisi shares in an open letter the ideas and perspectives behind the decision to join the EBWorld universe, both for Kode and our clients. Read more: https://lnkd.in/dPV-if56

We're delighted to share the deep dive by Galileo Research Srl about the presentation by our chemoinformatician Nedra Mekni, PhD at GAM - Galileo Annual Meeting. Nedra explained what impact #AI and #ComputationalChemistry are having on drug discovery and showed how solutions we're developing in Kode will streamline the #DrugDiscovery pipeline.

Last day to sign up for the free webinar about AI in Livestock Farming by CREA Ricerca and Università degli Studi di Padova 📆 14th of November from 5.00 pm to 6.10 pm Register Now: https://lnkd.in/ePf3bZSp Join us and discover the benefits and applications of AI in Animal Husbandry and take a deep dive into NIR spectroscopy with Spectralizer, the software by Kode to integrate spectroscopic analysis with production process control. Giovanni Cabassi Lorenzo Serva Marco Calderisi e Francesca Sbolgi #animalHusbandry #PrecisionLivestockFarming #NIR #spectroscopy #NIRspectroscopy #AI

🚀 FREE WEBINAR: AI meets Animal Husbandry 📆 Thursday 14th of November from 5.00 pm to 6.10 pm Register now: https://lnkd.in/ePf3bZSp Among the speakers: Giovanni Cabassi di CREA Ricerca Lorenzo Serva di Università degli Studi di Padova Marco Calderisi e Francesca Sbolgi di Kode 📣 In the context of the NIRVanA project (NIR Spectroscopy for the Benefit of Livestock Farming), our CEO Marco Calderisi and our Data Scientist Francesca Sbolgi will present #Spectralizer, the software we developed to analyse spectroscopic data, integrating it with process control, and its applications in the Animal Husbandry field. The NIRVanA project aims to disseminate information and knowledge about the benefits and proper use of portable and machine-mounted NIR spectroscopic equipment for dairy farms oriented towards Precision Livestock Farming (PLF) and small dairies, focused on the production of PDO (Protected Designation of Origin) cheeses. #animalHusbandry #PrecisionLivestockFarming #NIR #spectroscopy #NIRspectroscopy #AI

The new issue of the Kode newsletter is just around the corner, so sign up now and find out about the tangible benefits of data science and what's new in the world of #AI for #manufacturing #chemistry #sportsanalytics #mobility Subscribe now: https://lnkd.in/ddw_JeQC

⚛ Molecule in the spotlight ⚛ Breast cancer is a widespread and complex disease. Among the various subtypes of breast cancer, hormone receptor-positive (HR-positive), HER2-negative breast cancer is one of the most common. While endocrine therapies—which block hormone signals—are effective initially, some patients develop endocrine resistance. One of the key drivers of this resistance is mutations in the PIK3CA gene. This month's issue by our #Chemoinformatician Nedra Mekni, PhD explores the role of PIK3CA mutations in breast cancer, current treatment approaches, and the recent FDA approval of ITOVEBI (inavolisib), a new targeted therapy developed by Genentech Inc. Read the article at the link below #drugdesign #chemistry #biotechnology #chemoinformatics #breastcancer #cancer

Only a few days left until TEDxPisa ! The theme of the 2024 edition, #LuMe (a symbol of hope, knowledge, perseverance, and life), opens up wide and interesting inspirational speeches. Can't wait to be there: 📍 Arsenali della Repubblica, Pisa 📆 Sunday 27th October 2024, 2.30 PM

This morning at GAM - 2nd Galileo Annual Meeting organised by Galileo Research Srl - our chemoinformatician Nedra Mekni, PhD presented the scientific work she conducted with our Chemoinformatics BU Manager, Alessio Sommovigo, about a new pre-training framework developed for #DeNovo Design of drug-like molcules. In the realm of pharmaceutical development, discovering new therapeutic compounds is crucial for advancing medical treatments and addressing various health challenges. But such compounds exist within an extensive domain, hard to fully screen and test. We addressed the issue of how to efficiently navigate these search spaces to identify high-value subsets with the development of a generative model. This framework will be integral to future development tasks, including property prediction, thereby significantly enhancing its utility in drug discovery and development. We're thankful to Galileo Research for the opportunity to share this look at future in-silico solutions for labs and researches in the pharma field. #pharma #research #labs #insilico #qsar #drugdesign #medicaltreatments #RandD #AI #ArtificialIntelligence #generativemodels

#JoinNOW! Our #webinar with VIAVI Solutions about #RealTime #ProcessControl and how to make it a reality by integrating #AI and #NIR sensors in your production control systems is starting now! Don't miss out!