Cytomics memaparkan semula ini
🎊 ISEV proudly presents the latest version of the Minimal Requirements for Studies on Extracellular Vesicles (#MISEV2023, @ISEVcomms): https://buff.ly/49uaa2T 💪 This massive undertaking was lead by Joshua Welsh, Lorraine O'Driscoll, Deborah Goberdhan, Clotilde Théry and Kenneth Witwer, plus >1000 co-authors. What is MISEV2023? A thread: 👨🎓 MISEV2023 is a consensus document that provides recommendations and guidance on EV-related studies. MISEV2023 aims to enhance research design and reporting of experimental details, building on earlier MISEV editions. 🚫 MISEV is NOT a checklist of do’s and don’ts! MISEV is not a barrier to hamper innovation, a means to block publications, nor is MISEV a comprehensive list of literature. ✔️ MISEV aims to increase rigor, reproducibility, and transparency of EV studies, and covers the nomenclature, pre-processing variables, separation and characterization of EVs, and EV release, uptake and functions in vivo and in vitro. 📝 MISEV can be summarized by these questions: - What terms do you use and what do they mean? - From where did you obtain your EVs? - How did you separate, concentrate, characterize and store them? - How confidently can you prescribe a function or biomarker to EVs versus other components? - Have you shared your data and methods detailed enough to ensure replication? ✨ What’s new in MISEV2023? - How to approach non-vesicular extracellular particles? - Non-mammalian EV sources. - Technique-specific reporting for EV characterization. - EV release and uptake and in vivo EV studies. Massive congratulations to all lead authors and co-authors. Widely sharing this information, and following these guidelines is encouraged to improve the quality of EV-research!