DAB.bio

Bio-based Organic Acids: A Step Toward Sustainable Industry! The future of sustainable production of organic chemicals may hinge on bio-based organic acids, which offer a renewable route to products like textiles, food additives, and commodity chemicals. But there’s a catch: petrochemicals are still cheaper due to hurdles like high downstream processing (DSP) costs associated with the processing of diluted aqueous fermentation broths. How can we make bio-based organic acids more competitive? The answer may lie in reactive liquid-liquid extraction. This technique isolates organic acids into an organic phase, drastically reducing the volume that requires processing, intensifying the process and reducing DSP costs. One technology highlighted in this paper is our FAST™ technology - designed for efficient, continuous extraction and process intensification. FAST™ enables liquid-liquid extraction at scale, making bio-based production more cost-effective and sustainable. Read the full article to see how reactive extraction, empowered by FAST™, could transform the future of green manufacturing.

Don’t miss out on the presentation of our CEO Eric van der Meer today at 14:05!

Are you tuning in to Energy 2024 Conference?    Because DAB.bio will be!    Join our CEO, Eric van der Meer, for an inspirational session with numerous thought leaders on the challenges, breakthroughs and outlook for renewable fuels, including an insight in cost-effective biomanufacturing of fuels with our FAST™ technology.    Title: Cost-advantaged biomanufacturing – The journey of DAB.bio  Date: Wednesday, November 20th  Time: 14:05 – 14:25  Location: Online    Let’s shape the future of biomanufacturing together!    Christian Cuenot, Paul Groves Flying Forrest, Robert Kleibergen, Walter Pfeiffer Roland Berger, Wouter Meiring Shell, Ishan Rao, Ph.D. Syzygy Plasmonics, Maarten van Andel Actual-Energy 

“Failure is a product that doesn’t get on the market.”  But you could! Great article by Embriette Hyde in SynBioBeta insights, featuring Hendrik Waegeman, Head of Business Operations at Bio Base Europe Pilot Plant, on how they support startups worldwide to get to the market. BBEPP is helping companies overcome the "valley of death" by enabling them to efficiently scale their bio-based innovations without needing to invest in the hardware or technical expertise typically required. One major challenge remains: at commercial production scale, bio-based products must match synthetic counterparts in cost of product to drive adoption. As mentioned in the article, our scalable FAST™ biomanufacturing technology has demonstrated the ability to produce a fragrance molecule at a price level comparable to its fossil-based counterpart, which was performed in collaboration with BBEPP. What is your opinion on what is needed to bridge the price gap between bio and fossil-based products? How can industrial biotech successfully address this gap? Let us know in the comments. 

Our latest scientific paper is out now! In collaboration with the TU Delft, we have published a paper on the production of rose fragrance 2-phenylethanol (2PE), a compound often used in detergents and cosmetics. A huge thank you to Jean-Marc Daran and Marijke Luttik for the wonderful collaboration! Biomanufacturing at large scale is required to make the transition to a biobased economy, but adoption is often limited by costs, as a result of KPI’s such as productivity. This issue becomes even more pressing when you are trying to produce compounds that are toxic, such as 2PE. By continuously removing the toxic product from the fermentation with continuous liquid-liquid extraction, the aqueous concentration is kept at the desired level, dramatically improving productivity. This was shown in our pilot scale reactor at Bio Base Europe Pilot Plant with a strain developed at the TU Delft. We should mention the great scientists at DAB.bio that also contributed to the paper: Alessandro Brewster, Arjan Oudshoorn, Marion van Lotringen, Pieter Nelisse, Emily van den Berg Link to the paper in the comments. 

Must-attend event on biomanufacturing! DAB.bio very much enjoyed the opportunity to present its cutting-edge ISPR technology at yesterday’s Fermentation Based Manufacturing Symposium in Copenhagen. The industry is rightfully focused on the full spectrum of biotechnology - from feedstock to strain to fermentation technology to DSP and marketing. An integrated approach is the way to: -         Massively grow the 𝗩𝗢𝗟𝗨𝗠𝗘 of biomanufactured compounds -         Make the much needed 𝗜𝗠𝗣𝗔𝗖𝗧 on defossilisation Leveraging all available technologies, including innovations in manufacturing, allows us to manufacture at EUR/kg 5 now, with EUR/kg 2 in reach. Thanks DTU - Technical University of Denmark, The Fermentation Based Biomanufacturing Initiative Initiative, and Novo Nordisk Foundation for leading the way. In case you were not there, swipe to see some of our slides!

Are you present at the FBM symposium? Because DAB.bio will be! Join our CEO, Eric van der Meer, for an inspiring session on how DAB.bio’s FAST™ technology enables cost-effective biomanufacturing to allow the industry to meet its net-zero commitments. Title: Breaking the cost barrier in chemicals and fuels biomanufacturing with FAST™ continuous in-situ product removal. Date: Tuesday, October 22 Time: 14:20 – 14:40 Location: Studio 2, DR Byen, Copenhagen Let’s shape the future of biomanufacturing together! The Fermentation Based Biomanufacturing Initiative DTU - Technical University of Denmark

Auf Wiedersehen Munich! Our CEO Eric van der Meer and CCO Willem-Jan Meijer returned from an inspiring three days at Bits & Pretzels in Munich. An amazing event for the European tech community that is full of energy, with many exciting discussions between founders, investors and industry leaders and inspiring keynote sessions.  A must-attend for tech startups! 

The costs of biomanufacturing is still too high Is something we often hear. That is why we have developed the FAST technology – ISPR through continuous extraction. We recently published a flyer explaining the FAST technology. This flyer includes an in-silico comparison between a standard batch fermentation and a fermentation with the FAST technology. Compared to the batch fermentation, the FAST technology delivered: - 80% reduction in electricity usage  - 70% reduction in water usage  - 5x increase in volumetric productivity Enabling the production of more product from the same fermenter volume and resource-efficient and cost-effective biomanufacturing for you! More details on the FAST technology and the showcase can be found in the flyer on our website (link in comments). 

The costs of biomanufacturing is still too high Is something we often hear. That is why we have developed the FAST technology – ISPR through continuous extraction. We recently published a flyer explaining the FAST technology. This flyer includes an in-silico comparison between a standard batch fermentation and a fermentation with the FAST technology. Compared to the batch fermentation, the FAST technology delivered: - 80% reduction in electricity usage  - 70% reduction in water usage  - 5x increase in volumetric productivity Enabling the production of more product from the same fermenter volume and resource-efficient and cost-effective biomanufacturing for you! More details on the FAST technology and the showcase can be found in the flyer on our website (link in comments).