Single Cell Discoveries

🔬 Join the Future of Single-Cell Sequencing! 🔬 We’re excited to announce a new opening for the position of Senior Business Development Manger at Single Cell Discoveries! If you’re passionate about life sciences and B2B Sales, this opportunity is for you. In this role, as Senior Business Development Manager you will secure and retain business for SCD through professional, consultative, proactive sales activities focused on decision-makers and decision influencers at existing and new sponsors. What we offer is a fast-moving work environment where you will have responsibility and ownership to help our company grow. Join us in our mission to provide cutting-edge single-cell sequencing services for research, preclinical, and clinical development! We’re hashtag hashtag #hiring. Know anyone who might be interested? https://lnkd.in/dv6JERJu

🔬 Join the Future of Single-Cell Sequencing! 🔬 We’re excited to announce a new opening for the position of Account Executive at Single Cell Discoveries! If you’re passionate about life sciences and B2B Sales, this opportunity is for you. In this role, as Account Executive you will be responsible for client interactions, managing the sales process, and growing valuable client relationships. This is an exciting opportunity to channel your passion for Sales, Next Generation sequencing, and helping scientists find the right solution for their research. What we offer is a fast-moving work environment where you will have responsibility and ownership to help our company grow. Join us in our mission to provide cutting-edge single-cell sequencing services for research, preclinical, and clinical development! We’re hashtag #hiring. Know anyone who might be interested? https://lnkd.in/dS7cAZcH

📢 Our CEO Mauro Muraro will present single-cell & high-throughput RNA sequencing for Drug Discovery at the ELRIG UK Drug Discovery Forum in Paris tomorrow. He will discuss how adaptations to existing single-cell methods can accelerate the drug discovery pipeline by finding more and better targets. To learn more about Single Cell Discoveries and how we can help with your drug discovery process, feel free to contact Mauro tomorrow at the forum!

🔬 🦴 We are pleased to share a new publication by Xiaole Tong and colleagues in which they develop new human induced pluripotent stem cell (iPSC) lines! These lines are critical for isolating and tracking cells crucial for treating low back pain and osteoarthritis resulting from the breakdown of spinal discs and cartilage. Researchers created two stem cell lines with a special marker to identify cells that produce a key protein called aggrecan. Our Bulk RNA service was used to analyze gene expression profiles during chondrogenic differentiation. 📑 Check out the full study here: https://lnkd.in/ewuPxuHw

🎥 We co-hosted a webinar with Scale Biosciences on "CRISPR Screening at Scale," featuring their CRISPR enrichment kit with Darina Sikrova, R&D Scientist at Single Cell Discoveries, and Melanie Masuda, Director, Market Development at Scale Biosciences. This webinar highlighted how we can support your research through high-throughput CRISPRi screening, with a case study on glioblastoma spheroids. SCD offers expert guidance and cutting-edge tools to help you streamline workflows, and achieve high-resolution insights into gene regulatory networks. 🎥 Watch the webinar here: https://lnkd.in/ecvP9bNW 🔗 Read our blog to learn more Single-cell CRISPR (scCRISPR) screens here: https://lnkd.in/eP_rXRNp

In our latest blog, we delve into how high-throughput screening (HTS) is accelerating drug discovery 💊. As the demand for personalized medicine grows and chronic diseases become more prevalent, HTS is increasingly vital. This technology allows researchers to simultaneously evaluate thousands, or even millions, of compounds for their interactions with specific biological targets. 🔗 Read the blog to learn more about HTS: https://lnkd.in/eEv3jxuQ

We’re proud to have supported Priscilla F. Kerkman and colleagues in their immune response to the Staphylococcus aureus bacteremia study. Using our 10x Genomics service, they identified over 300 unique antibody sequences, discovering four monoclonal antibodies targeting S. aureus, with three cross-reacting with Staphylococcus epidermidis. This could lead to new therapeutic strategies against bacterial infections! 🔬 Read the full publication here: https://lnkd.in/evbVdBkh 🧬 Learn more about our 10x Genomics services: https://lnkd.in/emeR_x4a #Immunology #SingleCellSequencing 

🔬 Unlock unparalleled sensitivity and data quality with SORT-seq — your ultimate solution for analyzing complex samples, even with minimal cell input! SORT-seq is a cutting-edge single-cell RNA sequencing technology exclusively offered by Single Cell Discoveries. It is designed to handle a wide range of challenging cell types. Its unique FACS-based approach, combined with 384-well plates, allows it to process cells often incompatible with other platforms, such as 10x Genomics. 📖 Find out more in our SORT-seq info guide: https://lnkd.in/eB8tiMVt 📞 Find out how we can help your projects here: https://lnkd.in/ee6hS3xZ

As endorsed service providers of Scale Biosciences' kits, we can deliver high-throughput, cost-effective sequencing with advanced multiplexing and efficient workflows. We can utilize these flexible and scalable technologies to - Perform extensive sample multiplexing, even with low cell counts without complex preparation steps - Maintain a low multiplet rate of less than 5%, ensuring high-quality data and reliable results - Prepare up to 96 samples and 125,000-500,000 cells per run 🔗 Find out more about our Scale Biosciences' services: https://lnkd.in/evvxDq6t 📞 Wondering if this service is the most suitable option for you? Reach out to us to learn more: https://lnkd.in/eetA5fi5

🧪 Neutrophil profiling is infamously difficult due to short lifespan, sensitivity, and low RNA content. Given their biological significance and the complexity of global clinical trials, there is a pressing need for an easy-to-use stabilization protocol for single-cell RNA sequencing to enable neutrophil profiling. In our latest blog, we highlight a recent study by Roche evaluating three methods for neutrophil profiling. We also discuss how single-cell sequencing is reshaping drug discovery. 🔗 Check out the blog post here: https://lnkd.in/eeH98XnC