Default mode network activity and connectivity in psychopathology

S Whitfield-Gabrieli, JM Ford - Annual review of clinical …, 2012 - annualreviews.org
Neuropsychiatric disorders are associated with abnormal function of the default mode
network (DMN), a distributed network of brain regions more active during rest than during
performance of many attention-demanding tasks and characterized by a high degree of
functional connectivity (ie, temporal correlations between brain regions). Functional
magnetic resonance imaging studies have revealed that the DMN in the healthy brain is
associated with stimulus-independent thought and self-reflection and that greater …
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