Antinuclear antibodies (ANAs) are valuable laboratory markers to screen for and support
the diagnosis of various rheumatic diseases (known as ANA-associated rheumatic diseases). …

Idiopathic inflammatory myopathies (IIM) are a group of diseases characterized by immune-mediated
muscular lesions that may be associated with extra-muscular manifestations …

Background A phase 2 trial of tocilizumab showed preliminary evidence of efficacy in systemic
sclerosis. We assessed skin fibrosis and systemic sclerosis-associated interstitial lung …

Anti-transcription intermediary factor 1 (TIF1)-γ autoantibodies are robustly linked with
cancer-associated DM in adults. This review aims to give an overview of the physiological context …

Objectives To determine the causes of death and risk factors in systemic sclerosis (SSc).
Methods Between 2000 and 2011, we examined the death certificates of all French patients …

Dry powder inhalers (DPIs) are increasingly replacing metered dose inhalers in elderly chronic
obstructive pulmonary disease (COPD) patients. However, most DPIs are dependent on …

Objective To assess the safety and efficacy of rituximab in systemic sclerosis (SSc) in clinical
practice. Methods We performed a prospective study including patients with SSc from the …

There is currently no approved treatment for primary Sjögren’s syndrome, a disease that
primarily affects adult women. The difficulty in developing effective therapies is -in part- because …

Antisynthetase syndrome (ASSD) is a rare clinical condition that is characterized by the
occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung …

Objective Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes
early diagnosis and effective treatment, issues that may be addressed if patients could be …