Anticancer effects of different seaweeds on human colon and breast cancers
…, DH Lee, OG Manvoudou Pissibanganga, K Ko… - Marine drugs, 2014 - mdpi.com
Seafoods and seaweeds represent some of the most important reservoirs of new therapeutic
compounds for humans. Seaweed has been shown to have several biological activities, …
compounds for humans. Seaweed has been shown to have several biological activities, …
Plant biopharming of monoclonal antibodies
K Ko, H Koprowski - Virus Research, 2005 - Elsevier
Recent advances in molecular biology and plant biotechnology have shifted the concept of
growing crops as a food source to serving as a bioreactor for the production of therapeutic …
growing crops as a food source to serving as a bioreactor for the production of therapeutic …
Function and glycosylation of plant-derived antiviral monoclonal antibody
K Ko, Y Tekoah, PM Rudd, DJ Harvey… - Proceedings of the …, 2003 - National Acad Sciences
Plant genetic engineering led to the production of plant-derived mAb (mAb P ), which provides
a safe and economically feasible alternative to the current methods of antibody production …
a safe and economically feasible alternative to the current methods of antibody production …
Role of genetic factors and environmental conditions in recombinant protein production for molecular farming
A Jamal, K Ko, HS Kim, YK Choo, H Joung, K Ko - Biotechnology Advances, 2009 - Elsevier
Plants are generally considered to represent a promising heterologous expression system for
the production of valuable recombinant proteins. Minimal upstream plant production cost is …
the production of valuable recombinant proteins. Minimal upstream plant production cost is …
Plant-derived anti-Lewis Y mAb exhibits biological activities for efficient immunotherapy against human cancer cells
…, M Okulicz, D Deka, K Ko… - Proceedings of the …, 2006 - National Acad Sciences
Although current demands for therapeutic mAbs are growing quickly, production methods to
date, including in vitro mammalian tissue culture and transgenic animals, provide only …
date, including in vitro mammalian tissue culture and transgenic animals, provide only …
Co-transient expression of PSA-Fc and PAP-Fc fusion protein in plant as prostate cancer vaccine candidates and immune responses in mice
…, MK Kim, K Ko, YK Lee, DS Kim, SC Myung, K Ko - Plant Cell Reports, 2023 - Springer
Key message PAP-FcK and PSA-FcK prostate cancer antigenic proteins transiently co-expressed
in plant induce their specific humoral immune responses in mice. Abstract Prostate-…
in plant induce their specific humoral immune responses in mice. Abstract Prostate-…
Transgenic tomatoes expressing human beta-amyloid for use as a vaccine against Alzheimer's disease
JW Youm, JH Jeon, H Kim, YH Kim, K Ko, H Joung… - Biotechnology …, 2008 - Springer
Human β-amyloid (Aβ) is believed to be one of the main components of Alzheimer’s disease,
so reduction of Aβ is considered a key therapeutic target. Using Agrobacterium-mediated …
so reduction of Aβ is considered a key therapeutic target. Using Agrobacterium-mediated …
Expression of GA733‐Fc fusion protein as a vaccine candidate for colorectal cancer in transgenic plants
…, KA Hwang, SH Oh, YS Han, K Ko - BioMed Research …, 2012 - Wiley Online Library
The tumor‐associated antigen GA733 is a cell‐surface glycoprotein highly expressed in
colorectal carcinomas. In this study, 3 recombinant genes were constructed as follows: GA733 …
colorectal carcinomas. In this study, 3 recombinant genes were constructed as follows: GA733 …
Effect of untranslated leader sequence of AMV RNA 4 and signal peptide of pathogenesis-related protein 1b on attacin gene expression, and resistance to fire blight in …
K Ko, JL Norelli, JP Reynoird, E Boresjza-Wysocka… - Biotechnology …, 2000 - Springer
A cDNA clone of the gene encoding attacin was used to construct three plasmid binary vectors
in which attE was controlled by the cauliflower mosaic virus 35S promoter with duplicated …
in which attE was controlled by the cauliflower mosaic virus 35S promoter with duplicated …
Production of monoclonal antibodies in plants for cancer immunotherapy
G Moussavou, K Ko, JH Lee… - BioMed research …, 2015 - Wiley Online Library
Plants are considered as an alternative platform for recombinant monoclonal antibody (mAb)
production due to the improvement and diversification of transgenic techniques. The …
production due to the improvement and diversification of transgenic techniques. The …