MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease
…, J Rojas-Serrano, MI González-Pérez… - … England Journal of …, 2018 - Mass Medical Soc
Background Given the phenotypic similarities between rheumatoid arthritis (RA)–associated
interstitial lung disease (ILD) (hereafter, RA-ILD) and idiopathic pulmonary fibrosis, we …
interstitial lung disease (ILD) (hereafter, RA-ILD) and idiopathic pulmonary fibrosis, we …
Methotrexate and rheumatoid arthritis associated interstitial lung disease
…, MI González-Pérez… - European …, 2021 - Eur Respiratory Soc
Question addressed by the study Methotrexate (MTX) is a key anchor drug for rheumatoid
arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication of …
arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication of …
Influence of antisynthetase antibodies specificities on antisynthetase syndrome clinical spectrum time course
…, G Zampogna, MI Gonzalez Perez… - Journal of clinical …, 2019 - mdpi.com
Antisynthetase syndrome (ASSD) is a rare clinical condition that is characterized by the
occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung …
occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung …
The clinical phenotype of systemic sclerosis patients with anti-PM/Scl antibodies: results from the EUSTAR cohort
…, J DeVries-Bouwstra, MI Gonzalez-Perez… - …, 2021 - academic.oup.com
Objective To evaluate clinical associations of anti-PM/Scl antibodies in patients with SSc in
a multicentre international cohort, with particular focus on unresolved issues, including …
a multicentre international cohort, with particular focus on unresolved issues, including …
MUC5B promoter variant rs35705950 and rheumatoid arthritis associated interstitial lung disease survival and progression
…, J Rojas-Serrano, MI González-Pérez… - Seminars in arthritis and …, 2021 - Elsevier
Background The major risk factor for idiopathic pulmonary fibrosis (IPF), MUC5B rs35705950,
was found to be associated with rheumatoid arthritis-associated interstitial lung disease (…
was found to be associated with rheumatoid arthritis-associated interstitial lung disease (…
Evolution of pulmonary function in a cohort of patients with interstitial lung disease and positive for antisynthetase antibodies
MI González-Pérez, JG Mejía-Hurtado… - The Journal of …, 2020 - jrheum.org
Objective. To describe the evolution of the pulmonary function in patients with interstitial lung
disease (ILD) who are positive for at least 1 of the antisynthetase antibodies (ASAB) after …
disease (ILD) who are positive for at least 1 of the antisynthetase antibodies (ASAB) after …
Anti-Aminoacyl transfer-RNA-synthetases (Anti-tRNA) autoantibodies associated with interstitial lung disease: pulmonary disease progression has a persistent …
…, I Buendía-Roldán, MI González-Pérez… - Journal of Clinical …, 2020 - mdpi.com
Anti-tRNA autoantibodies are associated with interstitial lung disease (ILD), in at least two
clinical scenarios: the anti-synthetase syndrome (ASSD) and interstitial pneumonia with …
clinical scenarios: the anti-synthetase syndrome (ASSD) and interstitial pneumonia with …
Genetic Susceptibility to Antisynthetase Syndrome Associated With Single-Nucleotide Variants in the IL1B Gene That Lead Variation in IL-1β Serum Levels
…, E Ambrocio-Ortiz, MI González-Pérez… - Frontiers in …, 2020 - frontiersin.org
The antisynthetase syndrome (ASSD) is an autoimmune disorder characterized by myositis,
arthritis, mechanic's hands, fever, Raynaud phenomenon, and interstitial lung disease (ILD). …
arthritis, mechanic's hands, fever, Raynaud phenomenon, and interstitial lung disease (ILD). …
Interstitial lung disease progression in patients with anti-aminoacyl transfer-RNA-synthetase autoantibodies is characterized by higher levels of sCD163
…, I Buendía-Roldán, MI González-Pérez… - Immunology …, 2022 - Elsevier
Background Patients with anti-tRNA autoantibodies are characterized by arthritis, mechanics
hands, fever, Raynauds phenomenon, and interstitial lung disease (ILD), in at least two …
hands, fever, Raynauds phenomenon, and interstitial lung disease (ILD), in at least two …
Enhanced activity of NLRP3 inflammasome in the lung of patients with anti-synthetase syndrome
…, M Mejia, I Buendía-Roldán, MI González-Pérez… - Cells, 2022 - mdpi.com
Anti-synthetase syndrome (ASSD) is an autoimmune disorder characterized by inflammatory
interstitial lung disease (ILD). The main objective of this work was to quantify the …
interstitial lung disease (ILD). The main objective of this work was to quantify the …