SingHealth Duke-NUS AM Research Institute (AMRI)

“Lymphoma is a complex disease with over 80 subtypes. A big challenge is a need for improved understanding of the disease to enable early and accurate diagnosis. In SYMPHONY 2.0, we will deep dive into largely unstudied Asian-centric lymphomas and gather insights that will not only enable quicker diagnosis, it will help us improve our patients' outcomes,” - Prof Soon Thye LIM, CEO and Senior Consultant, NCCS   Are you curious about the latest advancements in lymphoma research? Hear from Prof Lim as he discusses SYMPHONY2.0, a research project recently awarded the NMRC's S$25M OF-LCG grant, dedicated to addressing the unique needs of Asian lymphoma patients.   For aspiring researchers, Prof Lim’s advice is clear: build a multidisciplinary team with skills in data science, biostatistics, and social sciences to bring diverse perspectives to the table. He encourages keeping the patient and the broader scientific community at the heart of research. Potential real-world applications and transformative insights are key to influencing standardised treatments, international policies, and treatment guidelines.   "Resilience and passion are key," says Prof Lim. "They'll drive you forward, even through inevitable setbacks."   Read more in our interview with Prof Lim: https://lnkd.in/g-9gPRTx   National Cancer Centre Singapore  Singapore General Hospital  Singapore National Eye Centre KK Women's and Children's Hospital SingHealth A*STAR - Agency for Science, Technology and Research Cancer Science Institute of Singapore  Nanyang Technological University Singapore  Lee Kong Chian School of Medicine  NUS Yong Loo Lin School of Medicine  National University of Singapore National University Hospital #AMRInews #AMRIcelebrates #NCCS #SGH #SNEC #KKH #ASTAR #CSI #NUS #NCIS #NUH #NTU #NMRC #OFLCG #cancer #lymphoma #SingHealth #AMC Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

Curious about why hypertension is rising despite better diagnosis, monitoring and treatment? Managing it remains a challenge, especially in primary care. Join Dr Prawira Oka, Clin Asst Prof Shiwaza Moosa and Clin Prof Chirk Jenn Ng Jenn as they share their #research findings on tackling this evidence-practice gap in hypertension and beyond. Sign up now at https://for.sg/rgr19feb or scan the QR code in the image below! SingHealth Polyclinics SingHealth #AMRIevents #research #RGR #hypertension #challenge #primarycare #familymedicine #Singapore #SHP #DukeNUS #SingHealth Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

Had a delightful chat with Lianhe Zaobao about my experiences in my neurosurgery and management roles, and my favourite food. I am immensely grateful to my colleagues and mentors at National Neuroscience Institute, Changi General Hospital and SingHealth who played a large role in shaping my career and personal journey. Through neurosurgery, I have encountered countless miracles, and as a leader, I get to build organisational culture and improve the lives of many more patients. Was also happy to share about my love for dinosaurs, taking things apart to find out how they work and why the human brain cannot handle multiple tasks at once. Thank you Lianhe Zaobao 联合早报 Poh Lay Hoon for this wonderful article.

#AMCDiscoveries Termination of Resuscitation (TOR) protocol enables emergency personnel to identify medically futile out-of-hospital cardiac arrest (OHCA) and terminate resuscitation efforts onsite. The TOR protocol was implemented in Singapore from 2019 onwards. Researchers from Changi General Hospital, Sengkang General Hospital, Singapore General Hospital and Duke-NUS Medical School evaluated the cost-effectiveness of the TOR protocol for OHCA management. The study adopted a healthcare provider’s perspective and a Markov model was developed to model the analysis. The study demonstrated the reduction in costs from the application of the TOR protocol, providing some justification for sustainable adoption. Read more in RESUSCITATION, Elsevier: https://lnkd.in/gXBNXEeM AMC researchers involved: Nuraini Nazeha, Nur Shahidah, Marcus Eng Hock Ong, Nick Graves, Ling Tiah, Nausheen E Doctor, Ivan Chua Collaborators: Dehang Hong (Singapore Civil Defence Force), Yih Yng Ng (Tan Tock Seng Hospital), Benjamin S H Leong (National University Hospital), Wei Ming Ng (Ng Teng Fong General Hospital), Desmond Renhao Mao (Khoo Teck Puat Hospital) #AMRInews #research #Markov #TOR #cardiacarrest #OHCA #CGH #SKH #SGH #DukeNUS #SingHealth #KTPH #SCDF #NUH #NTFGH #Singapore #AMC Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

#AMCDiscoveries Researchers from Singapore General Hospital and Duke-NUS Medical School examined the trajectory of estimated glomerular filtrate rate (eGFR), associated risk factors, and its relationship with end-stage kidney disease (ESKD) among a multiethnic patient population with type 2 diabetes in Singapore. Their study suggested that eGFR trajectories are correlated with multiple social and modifiable risk factors and inform the risk of ESKD. Read more in Journal of Diabetes, Wiley: https://bit.ly/4eFwpWD AMC researchers involved: Liang Feng, Yong Mong B., Kwek Jia Liang, Choong Meng Chan, Tazeen Jafar Collaborators: Xiuju Fu (A*STAR - Agency for Science, Technology and Research) #AMRInews #research #eGFR #ESKD #kidney #diabetes #SGH #DukeNUS #SingHealth #ASTAR #Singapore #AMC Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

#AMCDiscoveries Post-transplant or hematological cancer patients have a higher risk of mortality after infection with ancestral and early variants of severe acute respiratory syndrome (SARS)-CoV-2. Adoptive cell therapy (ACT) with virus-specific T cells (VSTs) could augment endogenous T cell immunity to avoid disease deterioration before viral clearance. Researchers from KK Women's and Children's Hospital and Duke-NUS Medical School conducted a phase I/II study (NCT04457726) where 13 adult and pediatric patients, acutely positive for SARS-CoV-2 and predicted to have a high chance of mortality, were recruited from September 2021 to February 2022. Twelve patients received a single dose of COVID-T cells, matched on at least 1 HLA. Based on their findings, long-acting third-party VSTs from convalescent or vaccinated donors could be expediently produced and might be clinically useful in future pandemics, particularly before global vaccination is implemented. Read more in Cytotherapy, Elsevier: https://bit.ly/3Nl5KlZ AMC researchers involved: Michaela Su-Fern Seng, King Pan NG , Thuan Tong Tan, Matthias Maiwald, Yeh Ching LINN, Wing Leung Collaborators: Teck Guan Soh, Lip Kun Tan (National University Hospital), Marieta Chan (Health Sciences Authority) #AMRInews #research #covid19 #SARS #cancer #adoptivecelltherapy #virusspecificTcells #KKH #DukeNUS #SingHealth #NUHS #HSA #Singapore #AMC Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

Excited for 2025? We’re thrilled to share our calendar of key #research events and commemorative days! Get ready to connect with the research community and stay informed on the latest research developments from the SingHealth Duke-NUS Academic Medical Centre. Make sure to save the calendar! #AMRIevents #calendarofevents #research #events #commemorativedays #2025 #research #Singapore #SingHealth #DukeNUS Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

Research Grand Rounds 2025 is back! Join us on 19 Feb to learn more about Translating Evidence into Real-world Practice: Challenges and Solutions from our SingHealth Polyclinics team! They will share their #research findings on tackling this evidence-practice gap in hypertension and beyond. Save the date and stay tuned for more details! Dr Prawira Oka Clin Asst Prof Shiwaza Moosa Clin Prof Chirk Jenn Ng SingHealth Polyclinics SingHealth #AMRIevents #research #RGR #hypertension #challenge #primarycare #familymedicine #Singapore #SHP #DukeNUS #SingHealth Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

AMRI wishes everyone a Happy New Year! We look forward to bringing you more news and information about our research in the coming year! #AMRI #research #singapore #happynewyear #2025 #research Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri

#ResearchGoals2025 Dr Allen Wong Wei Jiat, Consultant of SKH celebrates his favourite moment of 2024 – winning the SingHealth Publish Award! He’s set his sights to win it again in 2025, proving that excellence is a continuous journey fueled by dedication. Dr Wong lives by the best advice he has received, “Grit and passion are the key to success” - these values drive his unwavering commitment to #research. What have you set your sights on in 2025? Sengkang General Hospital SingHealth #AMRIcelebrates #newyearresolutions #goals #2025 #research #SingHealth #AMC #SKH Visit SingHealth Duke-NUS AM Research Institute (AMRI) at https://for.sg/aboutamri